Nipal1 NIPA-like domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nipal1provided by MGI
Official Full Name: NIPA-like domain containing 1provided by MGI
Primary source: MGI:MGI:1917951
See related: Ensembl:ENSMUSG00000067219 AllianceGenome:MGI:1917951
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Npal1; 3830408G10Rik
Summary: Predicted to enable magnesium ion transmembrane transporter activity. Involved in magnesium ion transport. Located in Golgi apparatus. Is expressed in cerebral cortex ventricular layer. Orthologous to human NIPAL1 (NIPA like domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in liver E18 (RPKM 8.6), placenta adult (RPKM 4.2) and 13 other tissues See more
Orthologs: human all
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Genomic context

Location:: 5 C3.2; 5 38.44 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (72805139..72828421)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (72647796..72671078)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.
Title: The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.

Submit: New GeneRIF Correction

General gene information

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Markers

D5Buc48 (e-PCR), detects polymorphism
- UniSTS:166276

NoName (e-PCR)
- UniSTS:235196

NoName (e-PCR)
- UniSTS:495810

NoName (e-PCR)
- UniSTS:487920

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables magnesium ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in magnesium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in magnesium ion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in magnesium ion transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: magnesium transporter NIPA3

Names: NIPA-like protein 1; non-imprinted in Prader-Willi/Angelman syndrome region protein 3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.