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    Il17c interleukin 17C [ Mus musculus (house mouse) ]

    Gene ID: 234836, updated on 27-Nov-2024

    Summary

    Official Symbol
    Il17cprovided by MGI
    Official Full Name
    interleukin 17Cprovided by MGI
    Primary source
    MGI:MGI:2446486
    See related
    Ensembl:ENSMUSG00000046108 AllianceGenome:MGI:2446486
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IL-17C
    Summary
    Enables cytokine activity. Acts upstream of or within neutrophil differentiation and positive regulation of cytokine production involved in inflammatory response. Located in extracellular space. Orthologous to human IL17C (interleukin 17C). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in spleen adult (RPKM 1.3), thymus adult (RPKM 0.9) and 22 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Il17c in Genome Data Viewer
    Location:
    8 E1; 8 71.03 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (123147912..123150820)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (122422020..122423639)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6697 Neighboring gene thyrotropin releasing hormone receptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E6698 Neighboring gene zinc finger CCCH-type containing 18 Neighboring gene STARR-positive B cell enhancer ABC_E9324 Neighboring gene STARR-positive B cell enhancer ABC_E8269 Neighboring gene STARR-positive B cell enhancer ABC_E1776 Neighboring gene cytochrome b-245, alpha polypeptide Neighboring gene predicted gene, 53466 Neighboring gene mevalonate (diphospho) decarboxylase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2)  1 citation

    General protein information

    Preferred Names
    interleukin-17C
    Names
    cytokine CX2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145834.5NP_665833.4  interleukin-17C

      Status: VALIDATED

      Source sequence(s)
      AL591003
      Consensus CDS
      CCDS90473.1
      UniProtKB/Swiss-Prot
      A6H6F0, Q8K4C5
      UniProtKB/TrEMBL
      A0A0R4J0P4
      Related
      ENSMUSP00000056008.4, ENSMUST00000050963.4
      Conserved Domains (1) summary
      pfam06083
      Location:88176
      IL17; Interleukin-17

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      123147912..123150820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153977.1XP_036009870.1  interleukin-17C isoform X1

      UniProtKB/Swiss-Prot
      A6H6F0, Q8K4C5
      Conserved Domains (1) summary
      pfam06083
      Location:108196
      IL17; Interleukin-17