Rn7sk RNA, 7SK, nuclear [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rn7skprovided by MGI
Official Full Name: RNA, 7SK, nuclearprovided by MGI
Primary source: MGI:MGI:103186
See related: Ensembl:ENSMUSG00002076161 AllianceGenome:MGI:103186
Gene type: snRNA
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Is expressed in central nervous system and sensory organ. Orthologous to human RN7SK (RNA component of 7SK nuclear ribonucleoprotein). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 9 E1; 9 43.63 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (78082584..78082915, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (78175302..78175633, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin.
Title: RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin.
Study shows the expression of Rn7SK increasing upon neuronal differentiation. Further data confirmed this finding in vivo upon knockdown of Rn7SK which blocked neuronal differentiation indicating an important role of 7SK in the acquisition of a neural fate.
Title: Rn7SK small nuclear RNA is involved in neuronal differentiation.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Rn7sk (e-PCR), detects polymorphism
- UniSTS:479030

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.