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    Snhg1 small nucleolar RNA host gene 1 [ Mus musculus (house mouse) ]

    Gene ID: 83673, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snhg1provided by MGI
    Official Full Name
    small nucleolar RNA host gene 1provided by MGI
    Primary source
    MGI:MGI:3763743
    See related
    AllianceGenome:MGI:3763743
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Acts upstream of or within response to bacterium. Is expressed in central nervous system; liver; retina; and skin. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver E14 (RPKM 101.2), liver E14.5 (RPKM 78.4) and 13 other tissues See more
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    Genomic context

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    See Snhg1 in Genome Data Viewer
    Location:
    19 A; 19 5.44 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8700851..8703690)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8723487..8726326)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cholinergic receptor, muscarinic 1, CNS Neighboring gene STARR-positive B cell enhancer ABC_E8737 Neighboring gene STARR-positive B cell enhancer ABC_E9454 Neighboring gene solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Neighboring gene STARR-positive B cell enhancer ABC_E1210 Neighboring gene predicted gene, 25855 Neighboring gene predicted gene, 25894 Neighboring gene predicted gene, 24452 Neighboring gene predicted gene, 24453 Neighboring gene predicted gene, 22744 Neighboring gene predicted gene, 22680 Neighboring gene predicted gene, 23246 Neighboring gene small nucleolar RNA, C/D box 22 Neighboring gene WD repeat domain 74 Neighboring gene testis expressed 54

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. lncRNA SNHG1 induced by SP1 regulates bone remodeling and angiogenesis via sponging miR-181c-5p and modulating SFRP1/Wnt signaling pathway. Yu X, et al. Mol Med, 2021 Nov 3. PMID 34732133, Free PMC Article
    2. Small nucleolar RNA host gene 1 silence inhibits the lipopolysaccharide-induced microglial apoptosis and inflammation. Shen H, et al. Cell Mol Biol (Noisy-le-grand), 2024 Mar 31. PMID 38650136
    3. LncRNA SNHG1 regulates cerebrovascular pathologies as a competing endogenous RNA through HIF-1α/VEGF signaling in ischemic stroke. Zhang L, et al. J Cell Biochem, 2018 Jul. PMID 29377234
    4. Long non-coding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) promote cell proliferation in colorectal cancer by affecting P53. Zhao Y, et al. Eur Rev Med Pharmacol Sci, 2018 Feb. PMID 29509245
    5. Long Noncoding RNA SNHG1 Promotes Neuroinflammation in Parkinson's Disease via Regulating miR-7/NLRP3 Pathway. Cao B, et al. Neuroscience, 2018 Sep 15. PMID 30031125

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy.
      Title: LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy.
    2. Small nucleolar RNA host gene 1 silence inhibits the lipopolysaccharide-induced microglial apoptosis and inflammation.
      Title: Small nucleolar RNA host gene 1 silence inhibits the lipopolysaccharide-induced microglial apoptosis and inflammation.
    3. Mechanisms underlying LncRNA SNHG1 regulation of Alzheimer's disease involve DNA methylation.
      Title: Mechanisms underlying LncRNA SNHG1 regulation of Alzheimer's disease involve DNA methylation.
    4. LncRNA SNHG1 Accelerates Cell Proliferation, Migration, and Invasion of Hepatoblastoma Through Mediating miR-6838-5p/PIM3/RhoA Axis.
      Title: LncRNA SNHG1 Accelerates Cell Proliferation, Migration, and Invasion of Hepatoblastoma Through Mediating miR-6838-5p/PIM3/RhoA Axis.
    5. Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
      Title: Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.
    6. LncRNA SNHG1 knockdown inhibits hyperglycemia induced ferroptosis via miR-16-5p/ACSL4 axis to alleviate diabetic nephropathy.
      Title: LncRNA SNHG1 knockdown inhibits hyperglycemia induced ferroptosis via miR-16-5p/ACSL4 axis to alleviate diabetic nephropathy.
    7. SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis.
      Title: SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis.
    8. LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1.
      Title: LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1.
    9. lncRNA SNHG1 induced by SP1 regulates bone remodeling and angiogenesis via sponging miR-181c-5p and modulating SFRP1/Wnt signaling pathway.
      Title: lncRNA SNHG1 induced by SP1 regulates bone remodeling and angiogenesis via sponging miR-181c-5p and modulating SFRP1/Wnt signaling pathway.
    10. Long non-coding RNA small nucleolar RNA host gene 1 alleviates the progression of recurrent spontaneous abortion via the microRNA-183-5p/ZEB2 axis.
      Title: Long non-coding RNA small nucleolar RNA host gene 1 alleviates the progression of recurrent spontaneous abortion via the microRNA-183-5p/ZEB2 axis.
    Submit: New GeneRIF Correction See all GeneRIFs (16)

    General gene information

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    Markers

    Other Names

    • small nucleolar RNA host gene (non-protein coding) 1

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002896.3 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AK043166

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      8700851..8703690
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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