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    Ccdc3 coiled-coil domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498795, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ccdc3provided by RGD
    Official Full Name
    coiled-coil domain containing 3provided by RGD
    Primary source
    RGD:1559473
    See related
    EnsemblRapid:ENSRNOG00000017933 AllianceGenome:RGD:1559473
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559473
    Summary
    Predicted to be involved in several processes, including negative regulation of gene expression; negative regulation of lipid metabolic process; and negative regulation of tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within negative regulation of lipid biosynthetic process; positive regulation of fat cell differentiation; and positive regulation of lipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular region. Orthologous to human CCDC3 (coiled-coil domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 42.7), Adrenal (RPKM 38.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ccdc3 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (77941148..78044820, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (73031891..73135173, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (76991722..77093515, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551092 Neighboring gene calcium/calmodulin-dependent protein kinase ID Neighboring gene uncharacterized LOC108348589 Neighboring gene uncharacterized LOC108348590 Neighboring gene uncharacterized LOC134482742 Neighboring gene optineurin

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    General protein information

    Preferred Names
    coiled-coil domain containing 3; coiled-coil domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432312.1NP_001419241.1  coiled-coil domain containing 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      D3ZAR0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      77941148..78044820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_574081.9XP_574081.4  coiled-coil domain-containing protein 3

      Related
      ENSRNOP00000024110.3, ENSRNOT00000024110.6
      Conserved Domains (1) summary
      pfam10211
      Location:184249
      Ax_dynein_light; Axonemal dynein light chain