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    Erich3 glutamate-rich 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295528, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Erich3provided by RGD
    Official Full Name
    glutamate-rich 3provided by RGD
    Primary source
    RGD:1593279
    See related
    EnsemblRapid:ENSRNOG00000009533 AllianceGenome:RGD:1593279
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in cytoplasm and non-motile cilium. Orthologous to human ERICH3 (glutamate rich 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 67.0), Brain (RPKM 33.2) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Erich3 in Genome Data Viewer
    Location:
    2q45
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (246275438..246377673)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (243615777..243717973)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (260947970..261049973)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S7 pseudogene Neighboring gene crystallin zeta Neighboring gene uncharacterized LOC120100979 Neighboring gene uncharacterized LOC102555516 Neighboring gene transmembrane protein 14C pseudogene Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta, pseudogene 3 Neighboring gene TNNI3 interacting kinase Neighboring gene leucine rich repeat containing 53

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in non-motile cilium ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    glutamate-rich 3; glutamate-rich protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433090.1 → NP_001420019.1  glutamate-rich 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6G9B4

    2. NM_001433091.1 → NP_001420020.1  glutamate-rich 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      F1MA76

    3. NM_001433092.1 → NP_001420021.1  glutamate-rich 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    4. NM_001433093.1 → NP_001420022.1  glutamate-rich 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    5. NM_001433094.1 → NP_001420023.1  glutamate-rich 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    6. NM_001433095.1 → NP_001420024.1  glutamate-rich 3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    7. NM_001433096.1 → NP_001420025.1  glutamate-rich 3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    8. NM_001433097.1 → NP_001420026.1  glutamate-rich 3 isoform 8

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    9. NM_001433098.1 → NP_001420027.1  glutamate-rich 3 isoform 9

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    10. NM_001433099.1 → NP_001420028.1  glutamate-rich 3 isoform 10

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    11. NM_001433100.1 → NP_001420029.1  glutamate-rich 3 isoform 11

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HWQ6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      246275438..246377673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017591360.3 → XP_017446849.1  glutamate-rich protein 3 isoform X2

      Related
      ENSRNOP00000012638.8, ENSRNOT00000012638.9

    2. XM_017591359.3 → XP_017446848.1  glutamate-rich protein 3 isoform X1

      Related
      ENSRNOP00000082310.1, ENSRNOT00000100545.2

    3. XM_039103891.2 → XP_038959819.1  glutamate-rich protein 3 isoform X3

      Conserved Domains (3) summary
      COG5271
      Location:708 → 1089
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      TIGR00927
      Location:923 → 1199
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam15257
      Location:245 → 350
      DUF4590; Domain of unknown function (DUF4590)

    4. XM_063282934.1 → XP_063139004.1  glutamate-rich protein 3 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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