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    Fam107b family with sequence similarity 107, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498796, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fam107bprovided by RGD
    Official Full Name
    family with sequence similarity 107, member Bprovided by RGD
    Primary source
    RGD:1561482
    See related
    EnsemblRapid:ENSRNOG00000014886 AllianceGenome:RGD:1561482
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to act upstream of or within sensory perception of sound. Orthologous to human FAM107B (family with sequence similarity 107 member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 476.2), Testes (RPKM 259.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam107b in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79387795..79594165, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (74478608..74685027, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (78489667..78689933, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 4A Neighboring gene uncharacterized LOC134482744 Neighboring gene uncharacterized LOC102554651 Neighboring gene uncharacterized LOC108348592 Neighboring gene uncharacterized LOC120097880 Neighboring gene uncharacterized LOC120097879 Neighboring gene uncharacterized LOC134482747 Neighboring gene Myb/SANT DNA binding domain containing 7 Neighboring gene heat shock protein family A (Hsp70) member 14 Neighboring gene cerebral dopamine neurotrophic factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. White JK, et al. Cell, 2013 Jul 18. PMID 23870131, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within sensory perception of sound ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM107B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025034.2 → NP_001020205.1  protein FAM107B isoform 1

      See identical proteins and their annotated locations for NP_001020205.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A0A8I5ZR87, A6JM08
      Conserved Domains (1) summary
      pfam06625
      Location:9 → 120
      DUF1151; Protein of unknown function (DUF1151)

    2. NM_001401503.1 → NP_001388432.1  protein FAM107B isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A6JM08
      Related
      ENSRNOP00000085064.1, ENSRNOT00000105947.2

    3. NM_001429379.1 → NP_001416308.1  protein FAM107B isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      79387795..79594165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600646.3 → XP_017456135.1  protein FAM107B isoform X1

      Related
      ENSRNOP00000077094.1, ENSRNOT00000095863.2

    2. XM_063276704.1 → XP_063132774.1  protein FAM107B isoform X6

      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A6JM08

    3. XM_008771884.4 → XP_008770106.1  protein FAM107B isoform X6

      See identical proteins and their annotated locations for XP_008770106.1

      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A0A8I5ZR87, A6JM08
      Conserved Domains (1) summary
      pfam06625
      Location:9 → 120
      DUF1151; Protein of unknown function (DUF1151)

    4. XM_063276703.1 → XP_063132773.1  protein FAM107B isoform X6

      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A6JM08

    5. XM_008771880.4 → XP_008770102.1  protein FAM107B isoform X4

      UniProtKB/TrEMBL
      A0A8I6A9X6, A0A8L2QA46
      Related
      ENSRNOP00000020220.4, ENSRNOT00000020220.7
      Conserved Domains (1) summary
      pfam06625
      Location:38 → 150
      DUF1151; Protein of unknown function (DUF1151)

    6. XM_039096026.2 → XP_038951954.1  protein FAM107B isoform X3

      UniProtKB/TrEMBL
      A0A8I6A9X6
      Conserved Domains (1) summary
      pfam06625
      Location:64 → 175
      DUF1151; Protein of unknown function (DUF1151)

    7. XM_039096027.2 → XP_038951955.1  protein FAM107B isoform X6

      UniProtKB/Swiss-Prot
      Q5U4F3
      UniProtKB/TrEMBL
      A0A8I5ZR87, A6JM08
      Conserved Domains (1) summary
      pfam06625
      Location:9 → 120
      DUF1151; Protein of unknown function (DUF1151)

    8. XM_008771881.4 → XP_008770103.1  protein FAM107B isoform X5

      UniProtKB/TrEMBL
      A0A0G2JV46, A0A8I5ZR87
      Related
      ENSRNOP00000069346.1, ENSRNOT00000079260.3
      Conserved Domains (1) summary
      pfam06625
      Location:36 → 148
      DUF1151; Protein of unknown function (DUF1151)

    9. XM_017600647.3 → XP_017456136.1  protein FAM107B isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U4F3.1 GenPept UniProtKB/Swiss-Prot:Q5U4F3

    Gene LinkOut

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