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    Tmem14a transmembrane protein 14A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363206, updated on 27-Nov-2024

    Summary

    Symbol
    Tmem14aprovided by RGD
    Full Name
    transmembrane protein 14Aprovided by RGD
    Primary source
    RGD:1307710
    See related
    EnsemblRapid:ENSRNOG00000013238 AllianceGenome:RGD:1307710
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and regulation of heme biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in mitochondrial membrane. Orthologous to human TMEM14A (transmembrane protein 14A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 146.7), Adrenal (RPKM 104.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem14a in Genome Data Viewer
    Location:
    9q13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (31137011..31148794)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (23640594..23652379)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (27333956..27345612)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549948 Neighboring gene uncharacterized LOC102550123 Neighboring gene glutathione S-transferase alpha 3 like 1 Neighboring gene glutathione S-transferase alpha 3 Neighboring gene makorin ring finger protein 1, pseudogene 1 Neighboring gene uncharacterized LOC108351903

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108790.2NP_001102260.1  transmembrane protein 14A

      See identical proteins and their annotated locations for NP_001102260.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JJ92, A6JJ93, D3ZUB4
      Related
      ENSRNOP00000032359.4, ENSRNOT00000037489.6
      Conserved Domains (1) summary
      pfam03647
      Location:487
      Tmemb_14; Transmembrane proteins 14C

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      31137011..31148794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)