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    Nr2c2ap nuclear receptor 2C2-associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361128, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nr2c2approvided by RGD
    Official Full Name
    nuclear receptor 2C2-associated proteinprovided by RGD
    Primary source
    RGD:1561190
    See related
    EnsemblRapid:ENSRNOG00000022247 AllianceGenome:RGD:1561190
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in nucleoplasm. Orthologous to human NR2C2AP (nuclear receptor 2C2 associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 85.6), Kidney (RPKM 84.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nr2c2ap in Genome Data Viewer
    Location:
    16p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19322395..19324912, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19288454..19290940, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (21036648..21039481, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene myocyte enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X-associated ankyrin-containing protein Neighboring gene small nucleolar RNA SNORA17 Neighboring gene neurocan

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112689

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor 2C2-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001047104.2 → NP_001040569.1  nuclear receptor 2C2-associated protein isoform 1

      See identical proteins and their annotated locations for NP_001040569.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A6KA88, F7F4U7, Q4KM83
      Conserved Domains (1) summary
      cl02148
      Location:12 → 65
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

    2. NM_001399419.1 → NP_001386348.1  nuclear receptor 2C2-associated protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A0A8I6AI65, A6KA87
      Related
      ENSRNOP00000092769.1, ENSRNOT00000100734.2
      Conserved Domains (1) summary
      cl02148
      Location:12 → 65
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

    3. NM_001399420.1 → NP_001386349.1  nuclear receptor 2C2-associated protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016

    4. NM_001399421.1 → NP_001386350.1  nuclear receptor 2C2-associated protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      Related
      ENSRNOP00000056763.3, ENSRNOT00000060012.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      19322395..19324912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275508.1 → XP_063131578.1  nuclear receptor 2C2-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6AI65, A6KA87
    Nucleotide Protein Strain
    Heading Accession and Version

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