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    Btbd6 BTB domain containing 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690367, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Btbd6provided by RGD
    Official Full Name
    BTB domain containing 6provided by RGD
    Primary source
    RGD:1597323
    See related
    EnsemblRapid:ENSRNOG00000014693 AllianceGenome:RGD:1597323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in neurogenesis. Predicted to be active in cytosol. Orthologous to human BTBD6 (BTB domain containing 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 119.9), Adrenal (RPKM 109.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Btbd6 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (137879202..137881662)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (132058094..132060603)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137785662..137788442)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene jagged canonical Notch ligand 2 Neighboring gene nudix hydrolase 14 Neighboring gene BRF1 general transcription factor IIIB subunit Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC134479482 Neighboring gene uncharacterized LOC134479483

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis. Ahmed F, et al. Invest Ophthalmol Vis Sci, 2004 Sep. PMID 15326124
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC156832

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in neurogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein 6
    Names
    BTB (POZ) domain containing 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077683.2 → NP_001071151.2  BTB/POZ domain-containing protein 6

      Status: VALIDATED

      Source sequence(s)
      BC127548, BM386388, DV213761
      UniProtKB/TrEMBL
      A0A8I5ZW64, A6KBX4, F1M7U0
      Related
      ENSRNOP00000019768.5, ENSRNOT00000019768.7
      Conserved Domains (4) summary
      smart00225
      Location:138 → 237
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:243 → 349
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:130 → 233
      BTB; BTB/POZ domain
      pfam08005
      Location:394 → 537
      PHR; PHR domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      137879202..137881662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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