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    Spmap2 sperm microtubule associated protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299599, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spmap2provided by RGD
    Official Full Name
    sperm microtubule associated protein 2provided by RGD
    Primary source
    RGD:1309240
    See related
    EnsemblRapid:ENSRNOG00000007960 AllianceGenome:RGD:1309240
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Theg
    Summary
    Predicted to be involved in spermatogenesis. Predicted to be located in nucleus. Orthologous to human SPMAP2 (sperm microtubule associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 184.1) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spmap2 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (10777984..10788157)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (10127394..10137556)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (13013521..13023666)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene C2 calcium-dependent domain containing 4C Neighboring gene uncharacterized LOC134479817 Neighboring gene MIER family member 2 Neighboring gene phospholipid phosphatase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Insertional mutation of the murine kisimo locus caused a defect in spermatogenesis. Yanaka N, et al. J Biol Chem, 2000 May 19. PMID 10747865
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sperm microtubule associated protein 2
    Names
    testicular haploid expressed gene protein
    theg spermatid protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013102.2 → NP_001013120.1  sperm microtubule associated protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001013120.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6K902
      Related
      ENSRNOP00000044536.2, ENSRNOT00000042792.6
      Conserved Domains (1) summary
      pfam14912
      Location:212 → 270
      THEG; Testicular haploid expressed repeat

    2. NM_001430265.1 → NP_001417194.1  sperm microtubule associated protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q5XHX8
      UniProtKB/TrEMBL
      A6K900

    3. NM_001430266.1 → NP_001417195.1  sperm microtubule associated protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8I6AGA2, A6K901

    4. NM_001430267.1 → NP_001417196.1  sperm microtubule associated protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6K902

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      10777984..10788157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006240857.3 → XP_006240919.1  sperm microtubule associated protein 2 isoform X1

      Related
      ENSRNOP00000010549.4, ENSRNOT00000010549.9
      Conserved Domains (1) summary
      pfam14912
      Location:212 → 270
      THEG; Testicular haploid expressed repeat

    2. XM_063263162.1 → XP_063119232.1  sperm microtubule associated protein 2 isoform X3

    3. XM_006240858.5 → XP_006240920.1  sperm microtubule associated protein 2 isoform X2

      Related
      ENSRNOP00000091522.1, ENSRNOT00000104430.2
      Conserved Domains (1) summary
      pfam14912
      Location:188 → 246
      THEG; Testicular haploid expressed repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XHX8.2 GenPept UniProtKB/Swiss-Prot:Q5XHX8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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