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    Tex46 testis expressed 46 [ Mus musculus (house mouse) ]

    Gene ID: 67663, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tex46provided by MGI
    Official Full Name
    testis expressed 46provided by MGI
    Primary source
    MGI:MGI:1914913
    See related
    Ensembl:ENSMUSG00000036921 AllianceGenome:MGI:1914913
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930549C01Rik
    Summary
    Orthologous to human TEX46 (testis expressed 46). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 11.3) See more
    Orthologs
    human all
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    Genomic context

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    See Tex46 in Genome Data Viewer
    Location:
    4 D3; 4 68.92 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (136334313..136340590)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136607091..136613279)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 1D Neighboring gene leucine zipper protein 1 Neighboring gene lysine (K)-specific demethylase 1A Neighboring gene STARR-positive B cell enhancer ABC_E6238 Neighboring gene STARR-positive B cell enhancer mm9_chr4:136177240-136177540 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene lactamase, beta-like 1 Neighboring gene Eph receptor B2 Neighboring gene STARR-seq mESC enhancer starr_11765 Neighboring gene STARR-seq mESC enhancer starr_11766 Neighboring gene STARR-seq mESC enhancer starr_11767 Neighboring gene VISTA enhancer mm1494 Neighboring gene predicted gene, 52708

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida. Fujihara Y, et al. PNAS Nexus, 2024 Mar. PMID 38516277, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    testis-expressed protein 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026300.2 → NP_080576.1  testis-expressed protein 46

      See identical proteins and their annotated locations for NP_080576.1

      Status: PROVISIONAL

      Source sequence(s)
      AK016074
      Consensus CDS
      CCDS18808.1
      UniProtKB/TrEMBL
      A3KG95, Q9CPU3
      Related
      ENSMUSP00000038976.3, ENSMUST00000046647.3
      Conserved Domains (1) summary
      pfam17671
      Location:11 → 161
      DUF5531; Family of unknown function (DUF5531)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      136334313..136340590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250327.4 → XP_011248629.1  testis-expressed protein 46 isoform X1

      Conserved Domains (1) summary
      pfam17671
      Location:56 → 149
      DUF5531; Family of unknown function (DUF5531)
    Nucleotide Protein Strain
    Heading Accession and Version

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