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    Ptprk protein tyrosine phosphatase receptor type K [ Mus musculus (house mouse) ]

    Gene ID: 19272, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptprkprovided by MGI
    Official Full Name
    protein tyrosine phosphatase receptor type Kprovided by MGI
    Primary source
    MGI:MGI:103310
    See related
    Ensembl:ENSMUSG00000019889 AllianceGenome:MGI:103310
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PTPk; RPTPkappa
    Summary
    Enables protein tyrosine phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in several cellular components, including dendrite; neuronal cell body; and photoreceptor outer segment. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and vibrissa. Orthologous to human PTPRK (protein tyrosine phosphatase receptor type K). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 11.3), CNS E18 (RPKM 10.7) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ptprk in Genome Data Viewer
    Location:
    10 A4; 10 15.06 cM
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (27950406..28473393)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (28074820..28597397)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26152 Neighboring gene STARR-seq mESC enhancer starr_26154 Neighboring gene predicted gene 10145 Neighboring gene STARR-seq mESC enhancer starr_26157 Neighboring gene STARR-seq mESC enhancer starr_26158 Neighboring gene STARR-seq mESC enhancer starr_26159 Neighboring gene slowmo homolog 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_26161 Neighboring gene STARR-seq mESC enhancer starr_26163 Neighboring gene STARR-seq mESC enhancer starr_26164 Neighboring gene STARR-seq mESC enhancer starr_26167 Neighboring gene STARR-seq mESC enhancer starr_26168 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:28384986-28385169 Neighboring gene STARR-seq mESC enhancer starr_26169 Neighboring gene thymocyte selection associated Neighboring gene STARR-seq mESC enhancer starr_26170 Neighboring gene pyruvate dehydrogenase E1 alpha 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (7) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables gamma-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone H2AXY142 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein tyrosine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein tyrosine phosphatase activity, metal-dependent IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to UV ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to reactive oxygen species ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of keratinocyte proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in leading edge membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in photoreceptor outer segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    receptor-type tyrosine-protein phosphatase kappa
    Names
    R-PTP-kappa
    protein-tyrosine phosphatase kappa
    NP_001346284.1
    NP_001346285.1
    NP_033009.1
    XP_006512669.1
    XP_006512670.1
    XP_006512671.1
    XP_006512673.1
    XP_006512674.1
    XP_006512675.1
    XP_006512677.1
    XP_006512678.1
    XP_006512680.1
    XP_006512681.1
    XP_006512682.1
    XP_011241445.1
    XP_011241446.1
    XP_011241447.1
    XP_011241448.1
    XP_017169339.1
    XP_030100820.1
    XP_036011592.1
    XP_036011593.1
    XP_036011594.1
    XP_036011595.1
    XP_036011596.1
    XP_036011597.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359355.2NP_001346284.1  receptor-type tyrosine-protein phosphatase kappa isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
      Consensus CDS
      CCDS87975.1
      UniProtKB/TrEMBL
      A0A1W2P7Y1
      Related
      ENSMUSP00000151866.2, ENSMUST00000218276.2
      Conserved Domains (4) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd00047
      Location:9391172
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
    2. NM_001359356.2NP_001346285.1  receptor-type tyrosine-protein phosphatase kappa isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
      Consensus CDS
      CCDS87976.1
      UniProtKB/TrEMBL
      B2RRF0
      Related
      ENSMUSP00000151986.2, ENSMUST00000218359.2
      Conserved Domains (4) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd00047
      Location:9131146
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
    3. NM_001428766.1NP_001415695.1  receptor-type tyrosine-protein phosphatase kappa isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
    4. NM_001428767.1NP_001415696.1  receptor-type tyrosine-protein phosphatase kappa isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
    5. NM_001428768.1NP_001415697.1  receptor-type tyrosine-protein phosphatase kappa isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
    6. NM_001428769.1NP_001415698.1  receptor-type tyrosine-protein phosphatase kappa isoform 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
    7. NM_008983.3NP_033009.1  receptor-type tyrosine-protein phosphatase kappa isoform 2 precursor

      See identical proteins and their annotated locations for NP_033009.1

      Status: VALIDATED

      Source sequence(s)
      AC129772, AC152983, AC153972, AC158646, AC159504
      Consensus CDS
      CCDS35874.1
      UniProtKB/Swiss-Prot
      P35822
      Related
      ENSMUSP00000126279.2, ENSMUST00000166468.2
      Conserved Domains (9) summary
      cd06263
      Location:35191
      MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00194
      Location:8981158
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd00047
      Location:9251158
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:487588
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293371
      fn3; Fibronectin type III domain
      pfam00102
      Location:12181452
      Y_phosphatase; Protein-tyrosine phosphatase
      cl11960
      Location:203283
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      27950406..28473393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243143.4XP_011241445.1  receptor-type tyrosine-protein phosphatase kappa isoform X5

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12601465
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8961174
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    2. XM_011243146.4XP_011241448.1  receptor-type tyrosine-protein phosphatase kappa isoform X23

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12541459
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8961168
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    3. XM_036155700.1XP_036011593.1  receptor-type tyrosine-protein phosphatase kappa isoform X8

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12561461
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cl28904
      Location:8921170
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    4. XM_006512606.4XP_006512669.1  receptor-type tyrosine-protein phosphatase kappa isoform X1

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12751480
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:9111189
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    5. XM_006512608.5XP_006512671.1  receptor-type tyrosine-protein phosphatase kappa isoform X4

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12691474
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:9111183
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    6. XM_006512607.4XP_006512670.1  receptor-type tyrosine-protein phosphatase kappa isoform X3

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12711476
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:9071185
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    7. XM_006512610.4XP_006512673.1  receptor-type tyrosine-protein phosphatase kappa isoform X6

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12591464
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8951173
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    8. XM_006512611.5XP_006512674.1  receptor-type tyrosine-protein phosphatase kappa isoform X9

      Conserved Domains (6) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd00063
      Location:487588
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14636
      Location:12531458
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:296370
      fn3; Fibronectin type III domain
      cl28904
      Location:8951167
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    9. XM_036155699.1XP_036011592.1  receptor-type tyrosine-protein phosphatase kappa isoform X7

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12571462
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cl28904
      Location:8931171
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    10. XM_036155701.1XP_036011594.1  receptor-type tyrosine-protein phosphatase kappa isoform X11

      Conserved Domains (6) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd14636
      Location:12511456
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cd00096
      Location:209219
      Ig; Ig strand B [structural motif]
      cl28904
      Location:8931165
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    11. XM_036155703.1XP_036011596.1  receptor-type tyrosine-protein phosphatase kappa isoform X14

      Conserved Domains (6) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd14636
      Location:12451450
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cd00096
      Location:209219
      Ig; Ig strand B [structural motif]
      cl28904
      Location:8811159
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    12. XM_006512612.4XP_006512675.1  receptor-type tyrosine-protein phosphatase kappa isoform X10

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12511456
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8871165
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    13. XM_030244960.2XP_030100820.1  receptor-type tyrosine-protein phosphatase kappa isoform X15

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12411446
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8831155
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    14. XM_006512614.5XP_006512677.1  receptor-type tyrosine-protein phosphatase kappa isoform X17

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12291434
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8711143
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    15. XM_017313850.3XP_017169339.1  receptor-type tyrosine-protein phosphatase kappa isoform X2

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12741479
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:9101188
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    16. XM_011243144.4XP_011241446.1  receptor-type tyrosine-protein phosphatase kappa isoform X12

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12501455
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8861164
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    17. XM_036155702.1XP_036011595.1  receptor-type tyrosine-protein phosphatase kappa isoform X13

      Conserved Domains (6) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00410
      Location:201287
      IG_like; Immunoglobulin like
      cd14636
      Location:12461451
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cd00096
      Location:209219
      Ig; Ig strand B [structural motif]
      cl28904
      Location:8821160
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    18. XM_036155704.1XP_036011597.1  receptor-type tyrosine-protein phosphatase kappa isoform X16

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12401445
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487582
      fn3; Fibronectin type III domain
      cl28904
      Location:8821154
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    19. XM_006512615.5XP_006512678.1  receptor-type tyrosine-protein phosphatase kappa isoform X18

      Conserved Domains (5) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      cd14636
      Location:12281433
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
      cl28904
      Location:8701142
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    20. XM_006512618.5XP_006512681.1  receptor-type tyrosine-protein phosphatase kappa isoform X20

      UniProtKB/TrEMBL
      Q8C462
      Conserved Domains (3) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
    21. XM_011243145.4XP_011241447.1  receptor-type tyrosine-protein phosphatase kappa isoform X21

      UniProtKB/TrEMBL
      Q8C462
      Conserved Domains (3) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
    22. XM_006512619.4XP_006512682.1  receptor-type tyrosine-protein phosphatase kappa isoform X22

      UniProtKB/TrEMBL
      Q8C462
      Conserved Domains (3) summary
      smart00137
      Location:31191
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:201287
      IG; Immunoglobulin
      pfam00041
      Location:487580
      fn3; Fibronectin type III domain
    23. XM_006512617.2XP_006512680.1  receptor-type tyrosine-protein phosphatase kappa isoform X19

      Conserved Domains (5) summary
      smart00137
      Location:1115
      MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
      smart00409
      Location:125211
      IG; Immunoglobulin
      cd14636
      Location:11991404
      R-PTPc-K-2; PTP domain of receptor-type tyrosine-protein phosphatase K, repeat 2
      pfam00041
      Location:411504
      fn3; Fibronectin type III domain
      cl28904
      Location:8351113
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily