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    Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 76233, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dnttip1provided by MGI
    Official Full Name
    deoxynucleotidyltransferase, terminal, interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1923483
    See related
    Ensembl:ENSMUSG00000017299 AllianceGenome:MGI:1923483
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6430706C13Rik
    Summary
    Predicted to enable several functions, including enzyme activator activity; nucleosome binding activity; and protein homodimerization activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 32.6), CNS E14 (RPKM 24.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dnttip1 in Genome Data Viewer
    Location:
    2 H3; 2 85.27 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164587935..164610140)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164746015..164768220)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene serine protease inhibitor, Kunitz type 5 Neighboring gene WAP four-disulfide core domain 3 Neighboring gene STARR-seq mESC enhancer starr_06333 Neighboring gene STARR-positive B cell enhancer ABC_E417 Neighboring gene ubiquitin-conjugating enzyme E2C Neighboring gene troponin C2, fast

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2)  1 citation
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables enzyme activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone deacetylase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    deoxynucleotidyltransferase terminal-interacting protein 1
    Names
    tdIF1
    tdT-interacting factor 1
    terminal deoxynucleotidyltransferase-interacting factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133763.1NP_598524.1  deoxynucleotidyltransferase terminal-interacting protein 1

      See identical proteins and their annotated locations for NP_598524.1

      Status: PROVISIONAL

      Source sequence(s)
      BC003486
      Consensus CDS
      CCDS17054.1
      UniProtKB/Swiss-Prot
      Q99LB0
      UniProtKB/TrEMBL
      Q3THA4
      Related
      ENSMUSP00000017443.8, ENSMUST00000017443.14

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      164587935..164610140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)