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    Fam174b family with sequence similarity 174, member B [ Mus musculus (house mouse) ]

    Gene ID: 100038347, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam174bprovided by MGI
    Official Full Name
    family with sequence similarity 174, member Bprovided by MGI
    Primary source
    MGI:MGI:3698178
    See related
    Ensembl:ENSMUSG00000078670 AllianceGenome:MGI:3698178
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in Golgi organization. Predicted to be located in Golgi apparatus and plasma membrane. Is expressed in Meckel's cartilage; cortical plate; lung; and skeleton. Orthologous to human FAM174B (family with sequence similarity 174 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in lung adult (RPKM 67.0), heart adult (RPKM 55.0) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Fam174b in Genome Data Viewer
    Location:
    7 D1; 7 42.24 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (73390055..73426667)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (73740307..73776919)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Smad nuclear interacting protein 1 pseudogene Neighboring gene isopentenyl-diphosphate delta isomerase, pseudogene 4 Neighboring gene STARR-seq mESC enhancer starr_19198 Neighboring gene predicted gene, 30236 Neighboring gene inositol polyphosphate multikinase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC31276

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162532.1NP_001156004.1  membrane protein FAM174B precursor

      See identical proteins and their annotated locations for NP_001156004.1

      Status: VALIDATED

      Source sequence(s)
      AC136004, BC110691
      Consensus CDS
      CCDS52275.1
      UniProtKB/Swiss-Prot
      Q2NLC2, Q8K064
      Related
      ENSMUSP00000103080.3, ENSMUST00000107456.4
      Conserved Domains (1) summary
      pfam06679
      Location:28152
      DUF1180; Protein of unknown function (DUF1180)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      73390055..73426667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)