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    Rps9 ribosomal protein S9 [ Mus musculus (house mouse) ]

    Gene ID: 76846, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rps9provided by MGI
    Official Full Name
    ribosomal protein S9provided by MGI
    Primary source
    MGI:MGI:1924096
    See related
    Ensembl:ENSMUSG00000006333 AllianceGenome:MGI:1924096
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3010033P07Rik
    Summary
    A structural constituent of ribosome. Predicted to be involved in positive regulation of cell population proliferation; ribosomal small subunit biogenesis; and translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in several structures, including cerebral cortex; diaphragm; eye; genitourinary system; and soleus. Orthologous to human RPS9 (ribosomal protein S9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 388.6), liver E14 (RPKM 316.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rps9 in Genome Data Viewer
    Location:
    7 A1; 7 2.13 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (3707035..3709896)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (3703954..3706897)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene membrane bound O-acyltransferase domain containing 7 Neighboring gene tRNA splicing endonuclease subunit 34 Neighboring gene STARR-positive B cell enhancer ABC_E2812 Neighboring gene paired Ig-like receptor B Neighboring gene STARR-positive B cell enhancer mm9_chr7:3672088-3672388 Neighboring gene paired-Ig-like receptor A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Brilkova M, et al. Cell Rep, 2022 Sep 27. PMID 36170830
    2. Premature aging in mice with error-prone protein synthesis. Shcherbakov D, et al. Sci Adv, 2022 Mar 4. PMID 35235349, Free PMC Article
    3. Global Hypertranscription in the Mouse Embryonic Germline. Percharde M, et al. Cell Rep, 2017 Jun 6. PMID 28591571, Free PMC Article
    4. The FgfrL1 receptor is required for development of slow muscle fibers. Amann R, et al. Dev Biol, 2014 Oct 15. PMID 25172430
    5. The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome. Hao L, et al. Biol Reprod, 2009 May. PMID 19129515, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC4138

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 5.8S rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 5.8S rRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation regulator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribosomal subunit protein uS4
    Names
    40S ribosomal protein S9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419057.1 → NP_001405986.1  small ribosomal subunit protein uS4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC171680

    2. NM_001419058.1 → NP_001405987.1  small ribosomal subunit protein uS4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC171680

    3. NM_001419059.1 → NP_001405988.1  small ribosomal subunit protein uS4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC171680
      UniProtKB/Swiss-Prot
      Q3UBF1, Q6ZWN5, Q8K2D1
      Related
      ENSMUSP00000104265.2, ENSMUST00000108625.8

    4. NM_001419060.1 → NP_001405989.1  small ribosomal subunit protein uS4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC171680
      UniProtKB/Swiss-Prot
      Q3UBF1, Q6ZWN5, Q8K2D1

    5. NM_029767.3 → NP_084043.1  small ribosomal subunit protein uS4 isoform 1

      See identical proteins and their annotated locations for NP_084043.1

      Status: VALIDATED

      Source sequence(s)
      AC171680
      Consensus CDS
      CCDS20726.1
      UniProtKB/Swiss-Prot
      Q3UBF1, Q6ZWN5, Q8K2D1
      Related
      ENSMUSP00000006496.9, ENSMUST00000006496.15
      Conserved Domains (1) summary
      PTZ00155
      Location:11 → 177
      PTZ00155; 40S ribosomal protein S9; Provisional

    RNA

    1. NR_185013.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC171680
      Related
      ENSMUST00000146927.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      3707035..3709896
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6ZWN5.3 GenPept UniProtKB/Swiss-Prot:Q6ZWN5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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