U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zfp865 zinc finger protein 865 [ Mus musculus (house mouse) ]

    Gene ID: 319748, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp865provided by MGI
    Official Full Name
    zinc finger protein 865provided by MGI
    Primary source
    MGI:MGI:2442656
    See related
    Ensembl:ENSMUSG00000074405 AllianceGenome:MGI:2442656
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf865; 6430526N21Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF865 (zinc finger protein 865). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 26.9), adrenal adult (RPKM 25.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp865 in Genome Data Viewer
    Location:
    7 A1; 7 2.9 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5023375..5036225)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5020376..5033226)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Flt3 interacting zinc finger protein 1 Neighboring gene STARR-seq mESC enhancer starr_17950 Neighboring gene zinc finger protein 524 Neighboring gene STARR-positive B cell enhancer ABC_E4889 Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 784 Neighboring gene zinc finger protein 580 Neighboring gene STARR-positive B cell enhancer ABC_E4890 Neighboring gene predicted gene 15510

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033383.2NP_001028555.1  zinc finger protein 865 isoform 1

      See identical proteins and their annotated locations for NP_001028555.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK154737
      Consensus CDS
      CCDS20753.1
      UniProtKB/Swiss-Prot
      D3Z3M5, Q3U3I9
      Related
      ENSMUSP00000075601.5, ENSMUST00000076251.7
      Conserved Domains (6) summary
      PHA03247
      Location:272343
      PHA03247; large tegument protein UL36; Provisional
      PHA03378
      Location:163349
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:349421
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:548568
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:441461
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:561584
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001290426.1NP_001277355.1  zinc finger protein 865 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC157563, AK051004, BY205386
      Consensus CDS
      CCDS71884.1
      UniProtKB/TrEMBL
      H9KUY5
      Related
      ENSMUSP00000082550.4, ENSMUST00000085427.6
      Conserved Domains (6) summary
      COG5048
      Location:349421
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:548568
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:666686
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:220242
      zf-C2H2; Zinc finger, C2H2 type
      pfam12446
      Location:272348
      DUF3682; Protein of unknown function (DUF3682)
      pfam13465
      Location:561583
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5023375..5036225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540059.3XP_006540122.1  zinc finger protein 865 isoform X2

      See identical proteins and their annotated locations for XP_006540122.1

      UniProtKB/Swiss-Prot
      D3Z3M5, Q3U3I9
      Conserved Domains (6) summary
      PHA03247
      Location:272343
      PHA03247; large tegument protein UL36; Provisional
      PHA03378
      Location:163349
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:349421
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:548568
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:441461
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:561584
      zf-H2C2_2; Zinc-finger double domain
    2. XM_017322300.3XP_017177789.1  zinc finger protein 865 isoform X3

      Conserved Domains (7) summary
      PHA03247
      Location:334405
      PHA03247; large tegument protein UL36; Provisional
      PHA03378
      Location:225411
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:411483
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:632683
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:610630
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:728748
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:623646
      zf-H2C2_2; Zinc-finger double domain
    3. XM_017322299.1XP_017177788.1  zinc finger protein 865 isoform X1

      Conserved Domains (6) summary
      PHA03247
      Location:334405
      PHA03247; large tegument protein UL36; Provisional
      PHA03378
      Location:225411
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:411483
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:610630
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:503523
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:623646
      zf-H2C2_2; Zinc-finger double domain
    4. XM_006540060.1XP_006540123.1  zinc finger protein 865 isoform X2

      See identical proteins and their annotated locations for XP_006540123.1

      UniProtKB/Swiss-Prot
      D3Z3M5, Q3U3I9
      Conserved Domains (6) summary
      PHA03247
      Location:272343
      PHA03247; large tegument protein UL36; Provisional
      PHA03378
      Location:163349
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:349421
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:548568
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:441461
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:561584
      zf-H2C2_2; Zinc-finger double domain