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    Brms1l breast cancer metastasis-suppressor 1-like [ Mus musculus (house mouse) ]

    Gene ID: 52592, updated on 9-Dec-2024

    Summary

    Official Symbol
    Brms1lprovided by MGI
    Official Full Name
    breast cancer metastasis-suppressor 1-likeprovided by MGI
    Primary source
    MGI:MGI:1196337
    See related
    Ensembl:ENSMUSG00000012076 AllianceGenome:MGI:1196337
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BRMS1; D12Ertd407e; 0710008O11Rik
    Summary
    Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1L (BRMS1 like transcriptional repressor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E18 (RPKM 23.2), frontal lobe adult (RPKM 20.6) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Brms1l in Genome Data Viewer
    Location:
    12 C1; 12 24.18 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (55883109..55916521)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (55836324..55869736)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene Ral GTPase activating protein, alpha subunit 1 Neighboring gene insulinoma-associated 2 Neighboring gene STARR-seq mESC enhancer starr_32196 Neighboring gene STARR-seq mESC enhancer starr_32197 Neighboring gene STARR-positive B cell enhancer ABC_E11776 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:56937027-56937210 Neighboring gene STARR-seq mESC enhancer starr_32198 Neighboring gene predicted gene, 22296 Neighboring gene predicted gene, 53722

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General protein information

    Preferred Names
    breast cancer metastasis-suppressor 1-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037756.3NP_001032845.1  breast cancer metastasis-suppressor 1-like protein

      See identical proteins and their annotated locations for NP_001032845.1

      Status: VALIDATED

      Source sequence(s)
      AK155742, BC034885
      Consensus CDS
      CCDS36453.1
      UniProtKB/Swiss-Prot
      Q3U1T3, Q8JZX8
      Related
      ENSMUSP00000082500.5, ENSMUST00000059250.8
      Conserved Domains (1) summary
      pfam08598
      Location:61179
      Sds3; Sds3-like

    RNA

    1. NR_155205.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159624, CR974464

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      55883109..55916521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_381530.4 RNA Sequence

    2. XR_004937525.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_027867.2: Suppressed sequence

      Description
      NM_027867.2: This RefSeq was permanently suppressed because it is a nonsense-mediated decay (NMD) candidate.