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    ZC8.6 Phosphatidylinositol 4-kinase type 2 [ Caenorhabditis elegans ]

    Gene ID: 180770, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZC8.6
    Official Full Name
    Phosphatidylinositol 4-kinase type 2
    Primary source
    WormBase:WBGene00022501
    Locus tag
    CELE_ZC8.6
    See related
    AllianceGenome:WB:WBGene00022501
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in Golgi organization; endosome organization; and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in membrane. Predicted to be active in endosome; plasma membrane; and trans-Golgi network. Orthologous to human PI4K2A (phosphatidylinositol 4-kinase type 2 alpha) and PI4K2B (phosphatidylinositol 4-kinase type 2 beta). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZC8.6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Sequence:
    Chromosome: X; NC_003284.9 (4972515..4997598, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Rootletin-like coiled-coil domain-containing protein Neighboring gene ncRNA Neighboring gene MYND-type domain-containing protein Neighboring gene 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. Gomes JE, et al. J Cell Biol, 2013 Aug 5. PMID 23918937, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol 4-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 1-phosphatidylinositol 4-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endosome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Phosphatidylinositol 4-kinase type 2
    NP_508849.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4972515..4997598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076448.8 → NP_508849.3  Phosphatidylinositol 4-kinase type 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508849.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23083
      Conserved Domains (1) summary
      cl21453
      Location:133 → 479
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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