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    pde-12 Endonuclease/exonuclease/phosphatase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176514, updated on 9-Dec-2024

    Summary

    Official Symbol
    pde-12
    Official Full Name
    Endonuclease/exonuclease/phosphatase domain-containing protein
    Primary source
    WormBase:WBGene00011268
    Locus tag
    CELE_R17.2
    See related
    AllianceGenome:WB:WBGene00011268
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable poly(A)-specific ribonuclease activity. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See pde-12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (10840005..10845020, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SMB domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene beta-N-acetylhexosaminidase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Endonuclease/exonuclease/phosphatase domain-containing protein
    NP_499388.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10840005..10845020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066987.5NP_499388.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499388.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18005
      Conserved Domains (1) summary
      cl00490
      Location:309628
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily