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    dylt-1 DYnein Light chain (Tctex type) [ Caenorhabditis elegans ]

    Gene ID: 172476, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dylt-1
    Official Full Name
    DYnein Light chain (Tctex type)
    Primary source
    WormBase:WBGene00008764
    Locus tag
    CELE_F13G3.4
    See related
    AllianceGenome:WB:WBGene00008764
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Is expressed in ADFL; ADFR; and intestine. Orthologous to human DYNLT1 (dynein light chain Tctex-type 1) and DYNLT3 (dynein light chain Tctex-type 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dylt-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (7300061..7300913, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class D (Delta) Neighboring gene Secreted protein Neighboring gene Glycosyltransferase family 92 protein;Glycosyltransferase family 92 protein F13G3.3 Neighboring gene Inositol monophosphatase ttx-7 Neighboring gene Glycosyltransferase 2-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The retrograde IFT machinery of C. elegans cilia: two IFT dynein complexes? Hao L, et al. PLoS One, 2011. PMID 21695221, Free PMC Article
    2. Insights on UNC-104-dynein/dynactin interactions and their implications on axonal transport in Caenorhabditis elegans. Chen CW, et al. J Neurosci Res, 2019 Feb. PMID 30311677
    3. A role for dynein in the inhibition of germ cell proliferative fate. Dorsett M, et al. Mol Cell Biol, 2009 Nov. PMID 19752194, Free PMC Article
    4. Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation. Deyter GM, et al. PLoS Genet, 2010 Nov 24. PMID 21124864, Free PMC Article
    5. Actin-dependent cytoplasmic streaming in C. elegans oogenesis. Wolke U, et al. Development, 2007 Jun. PMID 17507392

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DYnein Light chain (Tctex type)
    NP_492063.1
    • Product from WormBase gene class dylt;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7300061..7300913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059662.7 → NP_492063.1  DYnein Light chain (Tctex type) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492063.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19416
      Conserved Domains (1) summary
      pfam03645
      Location:7 → 105
      Tctex-1; Tctex-1 family
    Nucleotide Protein
    Heading Accession and Version

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