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    haps-1 Essential protein Yae1 N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172419, updated on 9-Dec-2024

    Summary

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    Official Symbol
    haps-1
    Official Full Name
    Essential protein Yae1 N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00016741
    Locus tag
    CELE_C48B6.3
    See related
    AllianceGenome:WB:WBGene00016741
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nucleus. Is expressed in germ line. Orthologous to human HAPSTR1 (HUWE1 associated protein modifying stress responses). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See haps-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (6915043..6916593)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class beta-15 Neighboring gene Serine/threonine-protein kinase smg-1 Neighboring gene U3 small nucleolar ribonucleoprotein imp3 Neighboring gene Protein pthb1 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome. Davy A, et al. EMBO Rep, 2001 Sep. PMID 11559592, Free PMC Article
    2. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
    3. C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways. Amici DR, et al. Proc Natl Acad Sci U S A, 2022 Jul 5. PMID 35776542, Free PMC Article
    4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    5. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Essential protein Yae1 N-terminal domain-containing protein
    NP_491971.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6915043..6916593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059570.7 → NP_491971.1  Essential protein Yae1 N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01512
      Conserved Domains (1) summary
      pfam15251
      Location:23 → 92
      DUF4588; Domain of unknown function (DUF4588)
    Nucleotide Protein
    Heading Accession and Version

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