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    axl-1 Axin-like protein 1 [ Caenorhabditis elegans ]

    Gene ID: 186869, updated on 2-Nov-2024

    Summary

    Official Symbol
    axl-1
    Official Full Name
    Axin-like protein 1
    Primary source
    WormBase:WBGene00010497
    Locus tag
    CELE_K02B12.4
    See related
    AllianceGenome:WB:WBGene00010497
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables protein kinase binding activity. Involved in axon guidance and negative regulation of Wnt signaling pathway. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See axl-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (8513900..8517535)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene Myb_DNA-bind_3 domain-containing protein Neighboring gene Tonsoku-like protein Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene ncRNA Neighboring gene FIP (Fungus-Induced Protein) Related

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    Axin-like protein 1
    NP_001040671.1
    • Partially confirmed by transcript evidence
    NP_001040672.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8513900..8517535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047207.6NP_001040672.1  Axin-like protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040672.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q14V27, Q3LRZ3
      Conserved Domains (2) summary
      cl02426
      Location:318386
      DIX; DIX domain
      cl02565
      Location:8115
      RGS; Regulator of G protein signaling (RGS) domain superfamily
    2. NM_001047206.5NP_001040671.1  Axin-like protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040671.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3LRZ3
      Conserved Domains (1) summary
      cl02426
      Location:249317
      DIX; DIX domain