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    F44A2.3 Lipid-binding serum glycoprotein C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179311, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F44A2.3
    Official Full Name
    Lipid-binding serum glycoprotein C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00018403
    Locus tag
    CELE_F44A2.3
    See related
    AllianceGenome:WB:WBGene00018403
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Predicted to be active in extracellular space. Is expressed in head; hypodermis; interfacial epithelial cell; and vulva. Orthologous to human BPIFC (BPI fold containing family C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F44A2.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    15
    Sequence:
    Chromosome: V; NC_003283.11 (9305416..9310926)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Lipid-binding serum glycoprotein C-terminal domain-containing protein
    NP_505406.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9305416..9310926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073005.7 → NP_505406.4  Lipid-binding serum glycoprotein C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505406.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20380
      Conserved Domains (1) summary
      cl00188
      Location:355 → 556
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
    Nucleotide Protein
    Heading Accession and Version

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