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    nas-38 Zinc metalloproteinase nas-38 [ Caenorhabditis elegans ]

    Gene ID: 180407, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nas-38
    Official Full Name
    Zinc metalloproteinase nas-38
    Primary source
    WormBase:WBGene00003554
    Locus tag
    CELE_F57C12.1
    See related
    AllianceGenome:WB:WBGene00003554
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metalloendopeptidase activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in extracellular region. Is expressed in hypodermis and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nas-38 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    17
    Sequence:
    Chromosome: X; NC_003284.9 (558157..563708)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Cerebellar degeneration-related protein 2-like Neighboring gene BHLH domain-containing protein Neighboring gene Multidrug resistance-associated protein 1 Neighboring gene Multidrug resistance-associated protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in PERK-mediated unfolded protein response HEP PubMed 
    involved_in molting cycle, collagen and cuticulin-based cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Zinc metalloproteinase nas-38
    NP_001359993.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      558157..563708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373215.2 → NP_001359993.1  Zinc metalloproteinase nas-38 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20942
      Conserved Domains (3) summary
      smart00042
      Location:367 → 466
      CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
      smart00209
      Location:613 → 658
      TSP1; Thrombospondin type 1 repeats
      pfam01400
      Location:122 → 313
      Astacin; Astacin (Peptidase family M12A)
    Nucleotide Protein
    Heading Accession and Version

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