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    rom-5 rhomboid protease [ Caenorhabditis elegans ]

    Gene ID: 190260, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rom-5
    Official Full Name
    rhomboid protease
    Primary source
    WormBase:WBGene00004404
    Locus tag
    CELE_Y54E10A.14
    See related
    AllianceGenome:WB:WBGene00004404
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rom-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (3217288..3222955, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DOMON domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene CDT1 Geminin-binding domain-containing protein Neighboring gene Thioredoxin-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid. Dutt A, et al. PLoS Biol, 2004 Nov. PMID 15455032, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal peptide processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rhomboid protease
    NP_001379293.1
    • Confirmed by transcript evidence
    NP_491125.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3217288..3222955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393189.1 → NP_001379293.1  rhomboid protease [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6V7QZA6
      Conserved Domains (1) summary
      cl21536
      Location:169 → 310
      Rhomboid; Rhomboid family

    2. NM_058724.6 → NP_491125.4  rhomboid protease [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491125.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3E5
      Conserved Domains (1) summary
      cl21536
      Location:161 → 302
      Rhomboid; Rhomboid family
    Nucleotide Protein
    Heading Accession and Version

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