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    col-35 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172492, updated on 2-Nov-2024

    Summary

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    Official Symbol
    col-35
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000612
    Locus tag
    CELE_C15A11.1
    See related
    AllianceGenome:WB:WBGene00000612
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See col-35 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003279.8 (7385907..7386935, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Paramyosin Neighboring gene Protein PXR1-like Neighboring gene ncRNA Neighboring gene Suppressor of lurcher protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrating transcriptomics and behavior tests reveals how the C. elegans responds to copper induced aging. Zhang Y, et al. Ecotoxicol Environ Saf, 2021 Oct 1. PMID 34265532
    2. In vitro mutagenesis of Caenorhabditis elegans cuticle collagens identifies a potential subtilisin-like protease cleavage site and demonstrates that carboxyl domain disulfide bonding is required for normal function but not assembly. Yang J, et al. Mol Cell Biol, 1994 Apr. PMID 8139571, Free PMC Article
    3. Structures and functions of collagens in Caenorhabditis elegans. Kramer JM. FASEB J, 1994 Mar 1. PMID 8143939
    4. Analysis of RING finger genes required for embryogenesis in C. elegans. Moore R, et al. Genesis, 2004 Jan. PMID 14755799
    5. The extracellular matrix phenome across species. Statzer C, et al. Matrix Biol Plus, 2020 Nov. PMID 33543035, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_492086.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7385907..7386935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059685.5 → NP_492086.3  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492086.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93208
      Conserved Domains (2) summary
      pfam01391
      Location:107 → 136
      Collagen; Collagen triple helix repeat (20 copies)
      pfam01484
      Location:12 → 60
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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