prp-21 uncharacterized protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: prp-21
Official Full Name: uncharacterized protein
Primary source: WormBase:WBGene00004188
Locus tag: CELE_W07E6.4
See related: AllianceGenome:WB:WBGene00004188
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Orthologous to human SF3A1 (splicing factor 3a subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See prp-21 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 9

Sequence:: Chromosome: II; NC_003280.10 (484866..490403)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W07E6.4 (e-PCR)
- UniSTS:311154

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA processing	IEA Inferred from Electronic Annotation more info
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in mRNA cis splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type prespliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein

NP_493746.1

Product from WormBase gene class prp;
Confirmed by transcript evidence; yeast PRP (splicing factor) related

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

484866..490403

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_061345.10 → NP_493746.1 uncharacterized protein CELE_W07E6.4 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_493746.1

Status: REVIEWED

UniProtKB/TrEMBL

G5ECL3

Conserved Domains (4) summary

cd01800
Location:580 → 655

SF3a120_C; Ubiquitin-like domain of Mammalian splicing factor SF3a_120

smart00648
Location:35 → 88

SWAP; Suppressor-of-White-APricot splicing regulator

smart00213
Location:577 → 648

UBQ; Ubiquitin homologues

pfam12230
Location:197 → 409

PRP21_like_P; Pre-mRNA splicing factor PRP21 like protein