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    Mageb2 MAGE family member B2 [ Mus musculus (house mouse) ]

    Gene ID: 17146, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mageb2provided by MGI
    Official Full Name
    MAGE family member B2provided by MGI
    Primary source
    MGI:MGI:105117
    See related
    Ensembl:ENSMUSG00000073069 AllianceGenome:MGI:105117
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Smage2; Mage-b2; Mage-rs2
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in testis. Orthologous to human MAGEB1 (MAGE family member B1); MAGEB6 (MAGE family member B6); and MAGEB6B (MAGE family member B6B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Mageb2 in Genome Data Viewer
    Location:
    X C2; X 40.35 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (90375511..90376503)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (91331905..91332897)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene heat shock protein 1 (chaperonin) pseudogene Neighboring gene tubulin, beta 6 pseudogene Neighboring gene PR domain containing 4 pseudogene Neighboring gene MAGE family member B6B1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MAGE family member B2
    Names
    melanoma antigen, family B, 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031171.1NP_112448.1  MAGE family member B2

      See identical proteins and their annotated locations for NP_112448.1

      Status: PROVISIONAL

      Source sequence(s)
      U19032
      Consensus CDS
      CCDS81151.1
      UniProtKB/TrEMBL
      Q4U221, Q6XZC3
      Related
      ENSMUSP00000098945.2, ENSMUST00000101397.2
      Conserved Domains (2) summary
      pfam01454
      Location:123276
      MAGE; MAGE family
      pfam12440
      Location:575
      MAGE_N; Melanoma associated antigen family N terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      90375511..90376503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)