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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_198483.4 → NP_940885.2 RUN and FYVE domain-containing protein 4
See identical proteins and their annotated locations for NP_940885.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the shorter transcript but encodes the supported protein. The exon combination of this variant lacks full-length support in human; it is predicted based on alignments of partial human transcripts and homologous transcripts from mouse GeneID:435626.
- Source sequence(s)
-
AC124768
- UniProtKB/Swiss-Prot
- Q6ZNE9, Q6ZR96
- UniProtKB/TrEMBL
-
C9J235
- Related
- ENSP00000513250.1, ENST00000697321.1
- Conserved Domains (4) summary
-
- cd15745
Location:520 → 562
- FYVE_RUFY4; FYVE-related domain found in RUN and FYVE domain-containing protein 4 (RUFY4) and similar proteins
- cd16269
Location:477 → 488
- GBP_C; coiled coil [structural motif]
- cl02689
Location:41 → 163
- RUN; RUN domain
- cl20817
Location:406 → 503
- GBP_C; Guanylate-binding protein, C-terminal domain
RNA
-
NR_034176.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) includes alternate exon structure in the 5' region and lacks an internal exon in the central region, compared to variant 1. This variant is represented as non-coding due to the presence of multiple upstream ORFs that are predicted to interfere with translation of the longest ORF; translation of these upstream ORFs would render the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC010136, AC124768, AK128393, AW452848, BX641664
- Related
-
ENST00000457754.6