U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    USE1 SNAP receptor USE1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852780, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    USE1
    Official Full Name
    SNAP receptor USE1
    Primary source
    SGD:S000003066
    Locus tag
    YGL098W
    See related
    AllianceGenome:SGD:S000003066; FungiDB:YGL098W; VEuPathDB:YGL098W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SLT1
    Summary
    Enables SNAP receptor activity. Involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Located in cytoplasmic side of endoplasmic reticulum membrane. Part of SNARE complex. Orthologous to human USE1 (unconventional SNARE in the ER 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See USE1 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (317342..318079)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative GTPase LSG1 Neighboring gene ncRNA Neighboring gene tRNA-His Neighboring gene Ran guanyl-nucleotide exchange factor

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Assembly-hub function of ER-localized SNARE proteins in biogenesis of tombusvirus replication compartment. Sasvari Z, et al. PLoS Pathog, 2018 May. PMID 29746582, Free PMC Article
    2. Structure of a membrane tethering complex incorporating multiple SNAREs. DAmico KA, et al. Nat Struct Mol Biol, 2024 Feb. PMID 38196032, Free PMC Article
    3. Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Tripathi A, et al. Nat Struct Mol Biol, 2009 Feb. PMID 19151722, Free PMC Article
    4. A SNARE required for retrograde transport to the endoplasmic reticulum. Burri L, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12893879, Free PMC Article
    5. Disruption and phenotypic analysis of six open reading frames from the left arm of Saccharomyces cerevisiae chromosome VII. Lillo JA, et al. Yeast, 2000 Mar 15. PMID 10669874

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables SNAP receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables SNAP receptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic side of endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    SNAP receptor USE1
    NP_011417.1
    • Essential SNARE protein localized to the ER; involved in retrograde traffic from the Golgi to the ER and Sey1p-independent homotypic ER fusion; required for efficient nuclear fusion during mating; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      317342..318079
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180963.1 → NP_011417.1  TPA: SNAP receptor USE1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011417.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VU47, P53146
      UniProtKB/TrEMBL
      A6ZU82, B3LHG3, B5VIM8, C7GM16, C8Z8F0, G2WE01, N1P349
      Conserved Domains (1) summary
      cd15860
      Location:151 → 210
      SNARE_USE1; SNARE motif of USE1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53146.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous