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    Ssna1 SS nuclear autoantigen 1 [ Mus musculus (house mouse) ]

    Gene ID: 68475, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ssna1provided by MGI
    Official Full Name
    SS nuclear autoantigen 1provided by MGI
    Primary source
    MGI:MGI:1915725
    See related
    Ensembl:ENSMUSG00000026966 AllianceGenome:MGI:1915725
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    N14; NA14; 1110003H09Rik; 1190004J23Rik
    Summary
    Enables identical protein binding activity. Involved in axon extension. Acts upstream of or within intraciliary transport and receptor clustering. Located in axon; centrosome; and ciliary basal body. Orthologous to human SSNA1 (SS nuclear autoantigen 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 39.9), liver E14.5 (RPKM 39.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ssna1 in Genome Data Viewer
    Location:
    2 A3; 2 17.12 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25161051..25162430, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25271039..25272418, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene NADPH dependent diflavin oxidoreductase 1 Neighboring gene transmembrane protein 203 Neighboring gene STARR-positive B cell enhancer ABC_E805 Neighboring gene taperin Neighboring gene anaphase promoting complex subunit 2 Neighboring gene transmembrane protein 210

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in axon arborization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axon arborization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in axon extension IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in axon extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axon extension ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axon extension ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell division ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within intraciliary transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in microtubule nucleation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within receptor clustering IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axoneme ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axoneme ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriole ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in supramolecular fiber ISO
    Inferred from Sequence Orthology
    more info
     
    located_in supramolecular fiber ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    microtubule nucleation factor SSNA1
    Names
    Sjogren's syndrome nuclear autoantigen 1
    sjoegren syndrome nuclear autoantigen 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023464.2NP_075953.1  microtubule nucleation factor SSNA1

      See identical proteins and their annotated locations for NP_075953.1

      Status: VALIDATED

      Source sequence(s)
      AL732309, BY703613
      Consensus CDS
      CCDS38071.1
      UniProtKB/Swiss-Prot
      Q9JJ94
      Related
      ENSMUSP00000028342.7, ENSMUST00000028342.7
      Conserved Domains (1) summary
      cl27170
      Location:697
      DUF460; Protein of unknown function (DUF460)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25161051..25162430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)