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    RTC4 Rtc4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855467, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RTC4
    Official Full Name
    Rtc4p
    Primary source
    SGD:S000005198
    Locus tag
    YNL254C
    See related
    AllianceGenome:SGD:S000005198; FungiDB:YNL254C; VEuPathDB:YNL254C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RTC4 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (168043..169248, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene trifunctional dihydropteroate synthetase/dihydrohydroxymethylpterin pyrophosphokinase/dihydroneopterin aldolase FOL1 Neighboring gene mRNA-binding translational activator GIS2 Neighboring gene Tex1p Neighboring gene mitochondrial 54S ribosomal protein YmL17/YmL30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The GIS2 Gene Is Repressed by a Zinc-Regulated Bicistronic RNA in Saccharomyces cerevisiae. Taggart J, et al. Genes (Basel), 2018 Sep 19. PMID 30235899, Free PMC Article
    2. Zap1-dependent transcription from an alternative upstream promoter controls translation of RTC4 mRNA in zinc-deficient Saccharomyces cerevisiae. Taggart J, et al. Mol Microbiol, 2017 Dec. PMID 28963784, Free PMC Article
    3. Putting the brake on FEAR: Tof2 promotes the biphasic release of Cdc14 phosphatase during mitotic exit. Waples WG, et al. Mol Biol Cell, 2009 Jan. PMID 18923139, Free PMC Article
    4. Systematic Screening of Penetratin's Protein Targets by Yeast Proteome Microarrays. Shah P, et al. Int J Mol Sci, 2022 Jan 10. PMID 35054898, Free PMC Article
    5. A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis. Louie RJ, et al. Genome Med, 2012 Dec 27. PMID 23270647, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rtc4p
    NP_014145.1
    • hypothetical protein; null mutation suppresses cdc13-1 temperature sensitivity; (GFP)-fusion protein localizes to both the cytoplasm and the nucleus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      168043..169248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183092.1 → NP_014145.1  TPA: Rtc4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014145.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5VQF5, C7GPA7, C8ZFY3, D6W0T9, P53850
      UniProtKB/TrEMBL
      N1NWY9
      Conserved Domains (1) summary
      pfam14474
      Location:218 → 364
      RTC4; RTC4-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53850.1

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