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    Actl9 actin-like 9 [ Mus musculus (house mouse) ]

    Gene ID: 69481, updated on 9-Dec-2024

    Summary

    Official Symbol
    Actl9provided by MGI
    Official Full Name
    actin-like 9provided by MGI
    Primary source
    MGI:MGI:1916731
    See related
    Ensembl:ENSMUSG00000092519 AllianceGenome:MGI:1916731
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700029I08Rik
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Involved in acrosome assembly and fertilization. Predicted to be located in acrosomal vesicle; perinuclear theca; and sperm head. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in several cellular components, including actin filament; axon; and synapse. Human ortholog(s) of this gene implicated in spermatogenic failure 53. Orthologous to human ACTL9 (actin like 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Actl9 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33651873..33653242)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33432899..33434268)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 81 Neighboring gene STARR-positive B cell enhancer mm9_chr17:33495732-33496033 Neighboring gene zinc finger protein 101 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33621106-33621293 Neighboring gene NFIL3 like basic leucine zipper Neighboring gene STARR-seq mESC enhancer starr_42406 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 10

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in acrosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in acrosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in fertilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in single fertilization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in acrosomal vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in perinuclear theca ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear theca ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sperm head ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm head ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    actin-like protein 9
    Names
    actin-like 7A; actin-like 7-alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183282.2NP_899105.2  actin-like protein 9

      See identical proteins and their annotated locations for NP_899105.2

      Status: PROVISIONAL

      Source sequence(s)
      BC089487, BU583640, BY083809, CN841548
      Consensus CDS
      CCDS57063.1
      UniProtKB/Swiss-Prot
      Q497R1, Q5EBK5, Q8CG27
      Related
      ENSMUSP00000134564.2, ENSMUST00000174088.3
      Conserved Domains (1) summary
      smart00268
      Location:48414
      ACTIN; Actin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33651873..33653242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)