Cox8b cytochrome c oxidase subunit 8B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cox8bprovided by MGI
Official Full Name: cytochrome c oxidase subunit 8Bprovided by MGI
Primary source: MGI:MGI:105958
See related: Ensembl:ENSMUSG00000025488 AllianceGenome:MGI:105958
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cox8h; CoxVIII-H
Summary: Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of respiratory chain complex IV. Is active in mitochondrial inner membrane. Is expressed in brown fat; heart; and tongue. Orthologous to human COX8BP (cytochrome c oxidase subunit 8B, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in heart adult (RPKM 359.9), adrenal adult (RPKM 147.9) and 4 other tissues See more
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Genomic context

Location:: 7 F5; 7 86.11 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (140478855..140480359, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (140898942..140900446, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (1)

General gene information

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Markers

Cox8b (e-PCR), detects polymorphism
- UniSTS:499083

Cox8b (e-PCR), detects polymorphism
- UniSTS:508564

AU019308 (e-PCR)
- UniSTS:159710

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: cytochrome c oxidase subunit 8B, mitochondrial

Names: COX VIII-H; cytochrome c oxidase polypeptide VIII-heart; cytochrome c oxidase subunit 8-1; cytochrome c oxidase subunit 8H; cytochrome c oxidase subunit VIII-H; cytochrome c oxidase subunit VIIIb

NP_031777.1

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.