Zfp747 zinc finger protein 747 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp747provided by MGI
Official Full Name: zinc finger protein 747provided by MGI
Primary source: MGI:MGI:2443581
See related: Ensembl:ENSMUSG00000054381 AllianceGenome:MGI:2443581
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 6430604K15Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Predicted to be involved in cellular response to glucocorticoid stimulus and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZNF764 (zinc finger protein 764). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in large intestine adult (RPKM 11.1), small intestine adult (RPKM 10.1) and 27 other tissues See more
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Genomic context

Location:: 7 F3; 7 69.48 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (126971709..126975222, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (127372537..127376050, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to glucocorticoid stimulus	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger protein 747

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175560.3 → NP_780769.1 zinc finger protein 747

See identical proteins and their annotated locations for NP_780769.1

Status: VALIDATED

Source sequence(s)

AK042972

Consensus CDS

CCDS40142.1

UniProtKB/TrEMBL

Q6PDC4, Q8BHM7

Related

ENSMUSP00000070685.5, ENSMUST00000067425.6

Conserved Domains (6) summary

smart00349
Location:22 → 81

KRAB; krueppel associated box

COG5048
Location:170 → 355

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:294 → 314

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:320 → 342

zf-C2H2; Zinc finger, C2H2 type

pfam01352
Location:22 → 61

KRAB; KRAB box

pfam13465
Location:167 → 191

zf-H2C2_2; Zinc-finger double domain