Psapl1 prosaposin-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Psapl1provided by MGI
Official Full Name: prosaposin-like 1provided by MGI
Primary source: MGI:MGI:1924193
See related: Ensembl:ENSMUSG00000043430 AllianceGenome:MGI:1924193
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2310020A21Rik
Summary: Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; prostate gland development; and regulation of lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in extracellular space. Is expressed in lower urinary tract; naris; rectum; and vibrissa. Orthologous to human PSAPL1 (prosaposin like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 5 B3; 5 19.14 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (36361365..36363912)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (36204021..36206568)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in epithelial cell differentiation involved in prostate gland development	IBA Inferred from Biological aspect of Ancestor more info
involved_in prostate gland growth	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of lipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sphingolipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: proactivator polypeptide-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175249.4 → NP_780458.3 proactivator polypeptide-like 1 precursor

Status: VALIDATED

Source sequence(s)

AC133937

Consensus CDS

CCDS39072.1

UniProtKB/Swiss-Prot

Q8BJV5, Q8C1C1, Q8C1N0

UniProtKB/TrEMBL

A0A0R4J1A5

Related

ENSMUSP00000100594.3, ENSMUST00000052224.7