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    S100a13 S100 calcium binding protein A13 [ Mus musculus (house mouse) ]

    Gene ID: 20196, updated on 9-Dec-2024

    Summary

    Official Symbol
    S100a13provided by MGI
    Official Full Name
    S100 calcium binding protein A13provided by MGI
    Primary source
    MGI:MGI:109581
    See related
    Ensembl:ENSMUSG00000042312 AllianceGenome:MGI:109581
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable several functions, including RAGE receptor binding activity; fibroblast growth factor binding activity; and metal ion binding activity. Predicted to be involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of interleukin-1 alpha production; and regulation of cell shape. Located in extracellular space. Is expressed in brown fat and heart. Orthologous to human S100A13 (S100 calcium binding protein A13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in mammary gland adult (RPKM 21.5), subcutaneous fat pad adult (RPKM 21.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See S100a13 in Genome Data Viewer
    Location:
    3 F1; 3 39.24 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90421542..90431888)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90514233..90524581)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene interleukin enhancer binding factor 2 Neighboring gene STARR-positive B cell enhancer ABC_E2084 Neighboring gene SNAP-associated protein Neighboring gene chromatin target of PRMT1 Neighboring gene STARR-positive B cell enhancer ABC_E2085 Neighboring gene STARR-seq mESC enhancer starr_08290 Neighboring gene S100 calcium binding protein A1 Neighboring gene S100 calcium binding protein A14 Neighboring gene S100 calcium binding protein A16

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RAGE receptor binding  
    enables RAGE receptor binding  
    enables calcium ion binding  
    enables calcium ion binding  
    enables calcium ion binding  
    enables calcium-dependent protein binding  
    enables copper ion binding  
    enables copper ion binding  
    enables fibroblast growth factor binding  
    enables lipid binding  
    enables protein homodimerization activity  
    enables zinc ion binding  
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix PubMed 
    located_in cytoplasm  
    located_in cytosol  
    located_in cytosol  
    is_active_in extracellular space  
    located_in extracellular space PubMed 
    located_in extracellular space  
    located_in extracellular space  
    located_in nucleolus  
    located_in nucleoplasm  
    located_in nucleus  
    is_active_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  
    located_in plasma membrane  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001410528.1NP_001397457.1  protein S100-A13

      Status: VALIDATED

      Source sequence(s)
      AC160552
      UniProtKB/Swiss-Prot
      P97352
      UniProtKB/TrEMBL
      Q545H7
    2. NM_001410529.1NP_001397458.1  protein S100-A13

      Status: VALIDATED

      Source sequence(s)
      AC160552
      UniProtKB/Swiss-Prot
      P97352
      UniProtKB/TrEMBL
      Q545H7
      Related
      ENSMUSP00000160100.1, ENSMUST00000250017.1
    3. NM_009113.6NP_033139.3  protein S100-A13

      Status: VALIDATED

      Source sequence(s)
      AC160552
      UniProtKB/Swiss-Prot
      P97352
      UniProtKB/TrEMBL
      Q545H7
      Related
      ENSMUSP00000047737.9, ENSMUST00000048138.8
      Conserved Domains (1) summary
      cd05022
      Location:796
      S-100A13; S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      90421542..90431888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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