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    Umad1 UMAP1-MVP12 associated (UMA) domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 100036521, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Umad1provided by MGI
    Official Full Name
    UMAP1-MVP12 associated (UMA) domain containing 1provided by MGI
    Primary source
    MGI:MGI:3840148
    See related
    Ensembl:ENSMUSG00000089862 AllianceGenome:MGI:3840148
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm16039
    Summary
    Is expressed in central nervous system and retina. Orthologous to human UMAD1 (UBAP1-MVB12-associated (UMA) domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 8.0), kidney adult (RPKM 6.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Umad1 in Genome Data Viewer
    Location:
    6 A1; 6 3.53 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (8259288..8428767)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (8259288..8428767)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15112 Neighboring gene meiosis regulator for oocyte development Neighboring gene STARR-positive B cell enhancer ABC_E1064 Neighboring gene STARR-positive B cell enhancer mm9_chr6:8225128-8225429 Neighboring gene replication protein A3 Neighboring gene STARR-seq mESC enhancer starr_15115 Neighboring gene STARR-seq mESC enhancer starr_15116 Neighboring gene STARR-seq mESC enhancer starr_15117 Neighboring gene predicted gene, 46952 Neighboring gene lysyl-tRNA synthetase pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:8435517-8436018 Neighboring gene RIKEN cDNA A430035B10 gene Neighboring gene STARR-positive B cell enhancer ABC_E126 Neighboring gene predicted gene, 26075

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression patterns of SP1 and SP3 during mouse spermatogenesis: SP1 down-regulation correlates with two successive promoter changes and translationally compromised transcripts. Ma W, et al. Biol Reprod, 2008 Aug. PMID 18417714, Free PMC Article
    2. Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain. Cajigas I, et al. Development, 2021 Mar 15. PMID 33593819, Free PMC Article
    3. A molecular profile of a hematopoietic stem cell niche. Hackney JA, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12226475, Free PMC Article
    4. The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Cajigas I, et al. Mol Cell, 2018 Sep 20. PMID 30146317, Free PMC Article
    5. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Potential readthrough

    Included gene: Glcci1

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    UBAP1-MVB12-associated (UMA)-domain containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001302353.1 → NP_001289282.1  UBAP1-MVB12-associated (UMA)-domain containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001289282.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK009885, BQ176979, BQ829587, BY291850, CF165156
      Consensus CDS
      CCDS80487.1
      UniProtKB/TrEMBL
      E0CX23
      Related
      ENSMUSP00000124993.2, ENSMUST00000160705.8
      Conserved Domains (1) summary
      pfam07718
      Location:92 → 118
      Coatamer_beta_C; Coatomer beta C-terminal region

    2. NM_001302354.1 → NP_001289283.1  UBAP1-MVB12-associated (UMA)-domain containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001289283.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK009885, BQ176979, BY291850, CF165156
      Consensus CDS
      CCDS80488.1
      UniProtKB/TrEMBL
      E0CXP6, E0CZ38
      Related
      ENSMUSP00000124564.2, ENSMUST00000159433.8
      Conserved Domains (1) summary
      pfam07718
      Location:66 → 92
      Coatamer_beta_C; Coatomer beta C-terminal region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      8259288..8428767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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