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    glucose-6-phosphate 1-epimerase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855125, updated on 9-Dec-2024

    Summary

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    Official Full Name
    glucose-6-phosphate 1-epimerase
    Primary source
    SGD:S000004705
    Locus tag
    YMR099C
    See related
    AllianceGenome:SGD:S000004705; FungiDB:YMR099C; VEuPathDB:YMR099C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables glucose-6-phosphate 1-epimerase activity. Predicted to be involved in carbohydrate metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (463934..464827, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Atp25p Neighboring gene tRNA-Asp Neighboring gene Mub1p Neighboring gene ditrans,polycis-polyprenyl diphosphate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glucose-6-phosphate 1-epimerase from bakers' yeast: purification, properties and possible biological function. Wurster B, et al. Hoppe Seylers Z Physiol Chem, 1974 Mar. PMID 4215729
    2. Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase. Graille M, et al. J Biol Chem, 2006 Oct 6. PMID 16857670
    3. Trz1, the long form RNase Z from yeast, forms a stable heterohexamer with endonuclease Nuc1 and mutarotase. Ma M, et al. Biochem J, 2017 Oct 18. PMID 28899942
    4. Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Anderson JB, et al. Genetics, 2003 Apr. PMID 12702675, Free PMC Article
    5. A consensus of core protein complex compositions for Saccharomyces cerevisiae. Benschop JJ, et al. Mol Cell, 2010 Jun 25. PMID 20620961

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucose-6-phosphate 1-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucose-6-phosphate 1-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucose-6-phosphate 1-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    glucose-6-phosphate 1-epimerase
    NP_013817.1
    • Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase); likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      463934..464827 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182599.1 → NP_013817.1  TPA: glucose-6-phosphate 1-epimerase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013817.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZS2, Q03161
      UniProtKB/TrEMBL
      A6ZMF6, B3LLZ0, B5VPM6, C7GVD6, C8ZEV1, G2WKE7, N1P5I9
      Conserved Domains (1) summary
      COG0676
      Location:1 → 294
      YeaD; D-hexose-6-phosphate mutarotase [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03161.1

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