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    ARG7 glutamate N-acetyltransferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855084, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ARG7
    Official Full Name
    glutamate N-acetyltransferase
    Primary source
    SGD:S000004666
    Locus tag
    YMR062C
    See related
    AllianceGenome:SGD:S000004666; FungiDB:YMR062C; VEuPathDB:YMR062C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ECM40
    Summary
    Enables L-glutamate N-acetyltransferase activity. Involved in ornithine biosynthetic process. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ARG7 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (395054..396379, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene SAM complex subunit SAM37 Neighboring gene cleavage polyadenylation factor subunit RNA14 Neighboring gene Rim9p Neighboring gene Aep1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study. Maes D, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006 Dec 1. PMID 17142921, Free PMC Article
    2. The yeast ARG7 gene product is autoproteolyzed to two subunit peptides, yielding active ornithine acetyltransferase. Abadjieva A, et al. J Biol Chem, 2000 Apr 14. PMID 10753950
    3. Characterization of the Saccharomyces cerevisiae ARG7 gene encoding ornithine acetyltransferase, an enzyme also endowed with acetylglutamate synthase activity. Crabeel M, et al. Eur J Biochem, 1997 Dec 1. PMID 9428669
    4. Purification and characterization of ornithine acetyltransferase from Saccharomyces cerevisiae. Liu Y, et al. Eur J Biochem, 1995 Mar 1. PMID 7705341
    5. The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis. Pauwels K, et al. Eur J Biochem, 2003 Mar. PMID 12603335

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The crystals belong to space group P4, with unit-cell parameters a = b = 66.98, c = 427.09 A, and a data set was collected to 2.76 A.
      Title: Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables L-glutamate N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-glutamate N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-glutamate N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-arginine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ornithine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ornithine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutamate N-acetyltransferase
    NP_013778.1
    • Mitochondrial ornithine acetyltransferase; catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      395054..396379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182560.1 → NP_013778.1  TPA: glutamate N-acetyltransferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013778.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZMC1, B3LLV5, B5VPI9, C7GL62, C8ZER4, D6VZN6, Q04682, Q04728, Q09168
      UniProtKB/TrEMBL
      G2WKB0, N1NYP4
      Conserved Domains (1) summary
      TIGR00120
      Location:22 → 441
      ArgJ; glutamate N-acetyltransferase/amino-acid acetyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04728.1

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