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    Tmem238l transmembrane protein 238 like [ Mus musculus (house mouse) ]

    Gene ID: 71576, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem238lprovided by MGI
    Official Full Name
    transmembrane protein 238 likeprovided by MGI
    Primary source
    MGI:MGI:1918826
    See related
    Ensembl:ENSMUSG00000085683 AllianceGenome:MGI:1918826
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9130409J20Rik
    Summary
    Predicted to be involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Is expressed in bladder; urinary system; and urothelium of bladder. Orthologous to human TMEM238L (transmembrane protein 238 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in large intestine adult (RPKM 84.1), small intestine adult (RPKM 45.2) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem238l in Genome Data Viewer
    Location:
    11 B3; 11 40.59 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (66847368..66855842)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (66955092..66965016)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12298 Neighboring gene predicted gene, 29712 Neighboring gene STARR-seq mESC enhancer starr_29784 Neighboring gene phosphoinositide-interacting regulator of transient receptor potential channels Neighboring gene STARR-seq mESC enhancer starr_29786 Neighboring gene STARR-positive B cell enhancer ABC_E8414 Neighboring gene STARR-seq mESC enhancer starr_29788 Neighboring gene predicted gene 12299 Neighboring gene STARR-seq mESC enhancer starr_29789 Neighboring gene STARR-seq mESC enhancer starr_29791 Neighboring gene transmembrane protein 220

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
    2. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 238-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001388429.1 → NP_001375358.1  transmembrane protein 238-like

      Status: VALIDATED

      Source sequence(s)
      AL645988
      UniProtKB/TrEMBL
      A0A1B0GRQ8, A0A1B0GS74
      Related
      ENSMUSP00000147820.2, ENSMUST00000211300.2
      Conserved Domains (1) summary
      pfam15125
      Location:13 → 76
      TMEM238; TMEM238 protein family

    2. NM_001388430.1 → NP_001375359.1  transmembrane protein 238-like

      Status: VALIDATED

      Source sequence(s)
      AL645988
      UniProtKB/TrEMBL
      A0A1B0GRQ8, A0A1B0GS74
      Related
      ENSMUSP00000147625.2, ENSMUST00000150220.2
      Conserved Domains (1) summary
      pfam15125
      Location:13 → 76
      TMEM238; TMEM238 protein family

    RNA

    1. NR_130646.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL645988
      Related
      ENSMUST00000127166.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      66847368..66855842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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