DAK2 dihydroxyacetone kinase [Saccharomyces cerevisiae S288C] - Gene

Summary

Go to the top of the page Help

Official Symbol: DAK2
Official Full Name: dihydroxyacetone kinase
Primary source: SGD:S000001841
Locus tag: YFL053W
See related: AllianceGenome:SGD:S000001841; FungiDB:YFL053W; VEuPathDB:YFL053W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables glycerone kinase activity. Involved in glycerol to glycerone phosphate metabolic process. Predicted to be active in cytosol. Orthologous to human TKFC (triokinase and FMN cyclase). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See DAK2 in Genome Data Viewer

Location:: chromosome: VI

Exon count:: 1

Sequence:: Chromosome: VI; NC_001138.5 (23423..25198)

Chromosome VI - NC_001138.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables glycerone kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycerone kinase activity	IEA Inferred from Electronic Annotation more info
enables glycerone kinase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables glycerone kinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables phosphotransferase activity, alcohol group as acceptor	IEA Inferred from Electronic Annotation more info
enables triokinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in anaerobic glycerol catabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycerol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol to glycerone phosphate metabolic process	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: dihydroxyacetone kinase

NP_116602.1

EC 2.7.1.28

EC 2.7.1.29

Dihydroxyacetone kinase; required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001138.5 Reference assembly

Range

23423..25198

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179914.1 → NP_116602.1 TPA: dihydroxyacetone kinase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_116602.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VTH7, P43550

UniProtKB/TrEMBL

C7GY59, N1P4R0

Conserved Domains (1) summary

TIGR02361
Location:4 → 586

dak_ATP; dihydroxyacetone kinase, ATP-dependent