U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FUBP1 far upstream element binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 8880, updated on 10-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FUBP1provided by HGNC
    Official Full Name
    far upstream element binding protein 1provided by HGNC
    Primary source
    HGNC:HGNC:4004
    See related
    Ensembl:ENSG00000162613 MIM:603444; AllianceGenome:HGNC:4004
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FBP; FUBP; hDH V
    Summary
    The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
    Expression
    Ubiquitous expression in lymph node (RPKM 23.3), bone marrow (RPKM 20.3) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FUBP1 in Genome Data Viewer
    Location:
    1p31.1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (77944055..77979501, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (77782851..77818345, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (78409740..78444756, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene mitoguardin 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:78336231-78337101 Neighboring gene heat shock protein family E (Hsp10) member 1 pseudogene 25 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1222 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1005 Neighboring gene NEXN antisense RNA 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:78374978-78375131 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:78383688-78384887 Neighboring gene nexilin F-actin binding protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1006 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:78431300-78431502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1223 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1226 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1225 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1224 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1227 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1228 Neighboring gene DnaJ heat shock protein family (Hsp40) member B4 Neighboring gene nitrilase family member 2 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1229 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1230 Neighboring gene GIPC PDZ domain containing family member 2 Neighboring gene RNA, U6 small nuclear 1102, pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma. Duan J, et al. PLoS One, 2017. PMID 28076379, Free PMC Article
    2. Far upstream element-binding protein 1 and RNA secondary structure both mediate second-step splicing repression. Li H, et al. Proc Natl Acad Sci U S A, 2013 Jul 16. PMID 23818605, Free PMC Article
    3. Identification of human DNA helicase V with the far upstream element-binding protein. Vindigni A, et al. Nucleic Acids Res, 2001 Mar 1. PMID 11222755, Free PMC Article
    4. Far upstream element binding protein 1: a commander of transcription, translation and beyond. Zhang J, et al. Oncogene, 2013 Jun 13. PMID 22926519, Free PMC Article
    5. Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE. Khageh Hosseini S, et al. Biochem Pharmacol, 2017 Dec 15. PMID 29031818

    See all (198) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19.
      Title: Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19.
    2. FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
      Title: FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
    3. FUBP1 promotes the proliferation of lung squamous carcinoma cells and regulates tumor immunity through PD-L1.
      Title: FUBP1 promotes the proliferation of lung squamous carcinoma cells and regulates tumor immunity through PD-L1.
    4. FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/beta-catenin signaling.
      Title: FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/β-catenin signaling.
    5. Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc.
      Title: Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc.
    6. The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC.
      Title: The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC.
    7. TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
      Title: TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
    8. LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC.
      Title: LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC.
    9. FUBP1 mediates the growth and metastasis through TGFbeta/Smad signaling in pancreatic adenocarcinoma.
      Title: FUBP1 mediates the growth and metastasis through TGFβ/Smad signaling in pancreatic adenocarcinoma.
    10. Long non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p.
      Title: Long non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p.
    Submit: New GeneRIF Correction See all GeneRIFs (60)

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

    Go to the top of the page Help

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env HIV-1 gp120 downregulates the expression of far upstream element-binding protein in T-cell lines and umbilical cord blood mononuclear cells PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT acts_upstream_of_or_within regulation of gene expression TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    far upstream element-binding protein 1
    Names
    DNA helicase V
    FUSE binding protein 1
    epididymis secretory sperm binding protein
    far upstream element (FUSE) binding protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_033243.2 RefSeqGene

      Range
      4889..35692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_995

    mRNA and Protein(s)

    1. NM_001303433.2 → NP_001290362.1  far upstream element-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001290362.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC096948, AK300032, CB133133, DA113820, U05040
      UniProtKB/TrEMBL
      A0A1Z1G4M2, B4DT31, E9PCF5
      Conserved Domains (5) summary
      pfam09005
      Location:623 → 643
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:119 → 193
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:207 → 276
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:297 → 364
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:397 → 468
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    2. NM_001376055.1 → NP_001362984.1  far upstream element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733
      UniProtKB/TrEMBL
      A0A1Z1G4M2
      Conserved Domains (5) summary
      pfam09005
      Location:622 → 642
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:118 → 192
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:206 → 275
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:296 → 363
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:396 → 467
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    3. NM_001376056.1 → NP_001362985.1  far upstream element-binding protein 1 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733
      Consensus CDS
      CCDS90982.1
      UniProtKB/TrEMBL
      A0A1Z1G4M2, A0A994J3Q8
      Related
      ENSP00000515388.1, ENST00000703586.1
      Conserved Domains (5) summary
      pfam09005
      Location:601 → 621
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:97 → 171
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:185 → 254
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:275 → 342
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:375 → 446
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    4. NM_001376057.1 → NP_001362986.1  far upstream element-binding protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733
      UniProtKB/TrEMBL
      A0A1Z1G4M2
      Conserved Domains (5) summary
      pfam09005
      Location:601 → 621
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:97 → 171
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:185 → 254
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:275 → 342
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:375 → 446
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    5. NM_001410804.1 → NP_001397733.1  far upstream element-binding protein 1 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733
      Consensus CDS
      CCDS90984.1
      UniProtKB/TrEMBL
      A0A1Z1G4M2, C9JSZ1
      Related
      ENSP00000402630.2, ENST00000421641.2

    6. NM_003902.5 → NP_003893.2  far upstream element-binding protein 1 isoform 2

      See identical proteins and their annotated locations for NP_003893.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC096948, CB133133, DA113820, U05040
      Consensus CDS
      CCDS683.1
      UniProtKB/Swiss-Prot
      Q12828, Q96AE4
      UniProtKB/TrEMBL
      A0A1Z1G4M2
      Related
      ENSP00000359804.2, ENST00000370768.7
      Conserved Domains (2) summary
      pfam09005
      Location:602 → 622
      DUF1897; Domain of unknown function (DUF1897)
      cl00098
      Location:98 → 172
      KH-I; K homology (KH) RNA-binding domain, type I

    RNA

    1. NR_130152.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate internal exon, uses an alternate splice site in an internal exon, and differs in the 3' terminal region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC017247, DA113820

    2. NR_146539.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate internal exon, uses an alternate splice site in an internal exon, and differs in the 3' terminal region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AW295160, BC017247, BQ934904, DA113820

    3. NR_146540.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an alternate internal exon, and differs in the 3' terminal region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL532525, AW295160, BC017247, BQ934904

    4. NR_164755.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733

    5. NR_164756.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC096948, KF510733

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      77944055..77979501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047433487.1 → XP_047289443.1  far upstream element-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A1Z1G4M2, A0A994J3Q8

    2. XM_047433493.1 → XP_047289449.1  far upstream element-binding protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    3. XM_047433485.1 → XP_047289441.1  far upstream element-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    4. XM_047433492.1 → XP_047289448.1  far upstream element-binding protein 1 isoform X9

      UniProtKB/Swiss-Prot
      Q12828, Q96AE4
      UniProtKB/TrEMBL
      A0A1Z1G4M2

    5. XM_047433489.1 → XP_047289445.1  far upstream element-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    6. XM_017002739.2 → XP_016858228.1  far upstream element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1Z1G4M2
      Conserved Domains (5) summary
      pfam09005
      Location:623 → 643
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:119 → 193
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:207 → 276
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:297 → 364
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:397 → 468
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    7. XM_047433488.1 → XP_047289444.1  far upstream element-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A1Z1G4M2, B4DT31, E9PCF5

    8. XM_017002743.3 → XP_016858232.1  far upstream element-binding protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A1Z1G4M2, A0A384MDX9
      Related
      ENSP00000294623.4, ENST00000294623.8
      Conserved Domains (5) summary
      pfam09005
      Location:601 → 621
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:97 → 171
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:185 → 254
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:275 → 342
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:375 → 446
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    9. XM_047433491.1 → XP_047289447.1  far upstream element-binding protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    10. XM_017002740.3 → XP_016858229.1  far upstream element-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1Z1G4M2
      Conserved Domains (5) summary
      pfam09005
      Location:623 → 643
      DUF1897; Domain of unknown function (DUF1897)
      cd22478
      Location:119 → 193
      KH-I_FUBP1_rpt1; first type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22481
      Location:207 → 276
      KH-I_FUBP1_rpt2; second type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22484
      Location:297 → 364
      KH-I_FUBP1_rpt3; third type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins
      cd22487
      Location:397 → 468
      KH-I_FUBP1_rpt4; fourth type I K homology (KH) RNA-binding domain found in far upstream element-binding protein 1 (FUBP1) and similar proteins

    RNA

    1. XR_007064840.1 RNA Sequence

    2. XR_007064839.1 RNA Sequence

    3. XR_007064844.1 RNA Sequence

    4. XR_007064843.1 RNA Sequence

    5. XR_007064838.1 RNA Sequence

    6. XR_007064842.1 RNA Sequence

    7. XR_946790.4 RNA Sequence

    8. XR_001737517.3 RNA Sequence

    9. XR_001737514.3 RNA Sequence

    10. XR_007064841.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      77782851..77818345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054339463.1 → XP_054195438.1  far upstream element-binding protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    2. XM_054339457.1 → XP_054195432.1  far upstream element-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A1Z1G4M2, A0A994J3Q8

    3. XM_054339456.1 → XP_054195431.1  far upstream element-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    4. XM_054339462.1 → XP_054195437.1  far upstream element-binding protein 1 isoform X9

      UniProtKB/Swiss-Prot
      Q12828, Q96AE4
      UniProtKB/TrEMBL
      A0A1Z1G4M2

    5. XM_054339459.1 → XP_054195434.1  far upstream element-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    6. XM_054339458.1 → XP_054195433.1  far upstream element-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A1Z1G4M2, B4DT31, E9PCF5

    7. XM_054339453.1 → XP_054195428.1  far upstream element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    8. XM_054339461.1 → XP_054195436.1  far upstream element-binding protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A1Z1G4M2, A0A384MDX9

    9. XM_054339455.1 → XP_054195430.1  far upstream element-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    10. XM_054339452.1 → XP_054195427.1  far upstream element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    11. XM_054339460.1 → XP_054195435.1  far upstream element-binding protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    12. XM_054339454.1 → XP_054195429.1  far upstream element-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1Z1G4M2

    RNA

    1. XR_008486196.1 RNA Sequence

    2. XR_008486194.1 RNA Sequence

    3. XR_008486195.1 RNA Sequence

    4. XR_008486200.1 RNA Sequence

    5. XR_008486193.1 RNA Sequence

    6. XR_008486199.1 RNA Sequence

    7. XR_008486190.1 RNA Sequence

    8. XR_008486198.1 RNA Sequence

    9. XR_008486189.1 RNA Sequence

    10. XR_008486192.1 RNA Sequence

    11. XR_008486191.1 RNA Sequence

    12. XR_008486197.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96AE4.3 GenPept UniProtKB/Swiss-Prot:Q96AE4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools