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    Chd3 chromodomain helicase DNA binding protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 216848, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Chd3provided by MGI
    Official Full Name
    chromodomain helicase DNA binding protein 3provided by MGI
    Primary source
    MGI:MGI:1344395
    See related
    Ensembl:ENSMUSG00000018474 AllianceGenome:MGI:1344395
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Chd7; Prp7; Prp9-1; 2600010P09Rik
    Summary
    Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Acts upstream of or within chromatin organization. Part of NuRD complex. Is expressed in several structures, including cerebral cortex; early conceptus; genitourinary system; pancreas epithelium; and spleen. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 53.4), limb E14.5 (RPKM 46.3) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Chd3 in Genome Data Viewer
    Location:
    11 B3; 11 42.53 cM
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69234099..69260325, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69343273..69369499, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel, shaker-related subfamily, beta member 3 Neighboring gene ring finger protein 227 Neighboring gene predicted gene, 22442 Neighboring gene STARR-positive B cell enhancer ABC_E5240 Neighboring gene predicted gene, 32483 Neighboring gene STARR-positive B cell enhancer ABC_E7004 Neighboring gene cytochrome b5 domain containing 1 Neighboring gene transmembrane protein 88 Neighboring gene N(alpha)-acetyltransferase 38, NatC auxiliary subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Restricted expression of chromatin remodeling associated factor Chd3 during tooth root development. Date Y, et al. J Periodontal Res, 2012 Apr. PMID 21972924
    2. Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development. de Castro RO, et al. Epigenetics Chromatin, 2022 May 14. PMID 35568926, Free PMC Article
    3. The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development. Xie J, et al. PLoS One, 2020. PMID 32658897, Free PMC Article
    4. Mammalian chromodomain proteins: their role in genome organisation and expression. Jones DO, et al. Bioessays, 2000 Feb. PMID 10655032
    5. Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. Sillibourne JE, et al. Mol Biol Cell, 2007 Sep. PMID 17626165, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.
      Title: The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.
    2. results suggest that ZFH/Chd3 might play an important role in tooth root development and subsequent cementogenesis.
      Title: Restricted expression of chromatin remodeling associated factor Chd3 during tooth root development.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (4)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC40857

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP hydrolysis activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ATP-dependent chromatin remodeler activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP-dependent chromatin remodeler activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within chromatin organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spindle organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of NuRD complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of NuRD complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of NuRD complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    chromodomain-helicase-DNA-binding protein 3
    Names
    Mi-2 alpha
    NP_666131.3
    XP_006532943.1
    XP_006532944.1
    XP_006532945.1
    XP_006532946.1
    XP_006532947.1
    XP_006532948.1
    XP_006532949.1
    XP_006532950.1
    XP_006532951.1
    XP_006532952.1
    XP_006532953.1
    XP_017169944.1
    XP_017169945.1
    XP_030101674.1
    XP_036012459.1
    XP_036012460.1
    XP_036012461.1
    XP_036012462.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146019.4 → NP_666131.3  chromodomain-helicase-DNA-binding protein 3

      Status: VALIDATED

      Source sequence(s)
      AK045449, BC030435, BC060721, BM950040, BU702731, CJ119759
      Consensus CDS
      CCDS48825.2
      UniProtKB/TrEMBL
      B1AR17, F7C528
      Related
      ENSMUSP00000104301.2, ENSMUST00000108661.8
      Conserved Domains (11) summary
      smart00298
      Location:685 → 737
      CHROMO; Chromatin organization modifier domain
      cd00046
      Location:808 → 966
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      pfam00176
      Location:791 → 1087
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:1111 → 1226
      Helicase_C; Helicase conserved C-terminal domain
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1408
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 252
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1789 → 1960
      CHDCT2; CHDCT2 (NUC038) domain
      pfam16885
      Location:1627 → 1749
      CAC1F_C; Voltage-gated calcium channel subunit alpha, C-term

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      69234099..69260325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532881.2 → XP_006532944.1  chromodomain-helicase-DNA-binding protein 3 isoform X3

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:770 → 1324
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1588 → 1758
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:433 → 475
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:509 → 551
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:679 → 733
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:556 → 634
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:787 → 1018
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1429 → 1568
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1363 → 1406
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:199 → 252
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1789 → 1916
      CHDCT2; CHDCT2 (NUC038) domain

    2. XM_030245814.1 → XP_030101674.1  chromodomain-helicase-DNA-binding protein 3 isoform X7

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:761 → 1315
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1579 → 1749
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:424 → 466
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:500 → 542
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:670 → 724
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:547 → 625
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:778 → 1009
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1420 → 1559
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1354 → 1397
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1780 → 1907
      CHDCT2; CHDCT2 (NUC038) domain

    3. XM_006532882.2 → XP_006532945.1  chromodomain-helicase-DNA-binding protein 3 isoform X4

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:767 → 1321
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1585 → 1755
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:430 → 472
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:506 → 548
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:676 → 730
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:553 → 631
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:784 → 1015
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1426 → 1565
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1360 → 1403
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1786 → 1913
      CHDCT2; CHDCT2 (NUC038) domain

    4. XM_036156569.1 → XP_036012462.1  chromodomain-helicase-DNA-binding protein 3 isoform X14

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:765 → 1319
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1555 → 1740
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:428 → 470
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:504 → 546
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:674 → 728
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:551 → 629
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:782 → 1013
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1424 → 1563
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1360 → 1403
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1783 → 1909
      CHDCT2; CHDCT2 (NUC038) domain

    5. XM_006532883.2 → XP_006532946.1  chromodomain-helicase-DNA-binding protein 3 isoform X5

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:765 → 1319
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1583 → 1753
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:428 → 470
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:504 → 546
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:674 → 728
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:551 → 629
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:782 → 1013
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1424 → 1563
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1358 → 1401
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1784 → 1911
      CHDCT2; CHDCT2 (NUC038) domain

    6. XM_006532888.2 → XP_006532951.1  chromodomain-helicase-DNA-binding protein 3 isoform X16

      UniProtKB/TrEMBL
      E9Q614, F7C528
      Related
      ENSMUSP00000090649.7, ENSMUST00000092971.13
      Conserved Domains (11) summary
      TIGR02927
      Location:1572 → 1724
      SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1755 → 1926
      CHDCT2; CHDCT2 (NUC038) domain

    7. XM_017314456.2 → XP_017169945.1  chromodomain-helicase-DNA-binding protein 3 isoform X15

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      TIGR02927
      Location:1572 → 1725
      SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1756 → 1927
      CHDCT2; CHDCT2 (NUC038) domain

    8. XM_006532884.2 → XP_006532947.1  chromodomain-helicase-DNA-binding protein 3 isoform X10

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      TIGR02927
      Location:1572 → 1725
      SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1756 → 1883
      CHDCT2; CHDCT2 (NUC038) domain

    9. XM_006532880.2 → XP_006532943.1  chromodomain-helicase-DNA-binding protein 3 isoform X2

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1561 → 1746
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1789 → 1916
      CHDCT2; CHDCT2 (NUC038) domain

    10. XM_006532886.2 → XP_006532949.1  chromodomain-helicase-DNA-binding protein 3 isoform X12

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1589 → 1759
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1790 → 1961
      CHDCT2; CHDCT2 (NUC038) domain

    11. XM_017314455.2 → XP_017169944.1  chromodomain-helicase-DNA-binding protein 3 isoform X1

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1589 → 1759
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1790 → 1917
      CHDCT2; CHDCT2 (NUC038) domain

    12. XM_006532889.1 → XP_006532952.1  chromodomain-helicase-DNA-binding protein 3 isoform X17

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:551 → 1105
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1369 → 1539
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:214 → 256
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:290 → 332
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:460 → 514
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:337 → 415
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:568 → 799
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1210 → 1349
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1144 → 1187
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:1 → 33
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1570 → 1697
      CHDCT2; CHDCT2 (NUC038) domain

    13. XM_006532887.4 → XP_006532950.1  chromodomain-helicase-DNA-binding protein 3 isoform X13

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:716 → 1270
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1549 → 1704
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:379 → 421
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:455 → 497
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:625 → 679
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:502 → 580
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:733 → 964
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1375 → 1514
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1309 → 1352
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:145 → 198
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1735 → 1862
      CHDCT2; CHDCT2 (NUC038) domain

    14. XM_006532890.3 → XP_006532953.1  chromodomain-helicase-DNA-binding protein 3 isoform X18

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:770 → 1324
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1588 → 1758
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:433 → 475
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:509 → 551
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:679 → 733
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:556 → 634
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:787 → 1018
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1429 → 1568
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1363 → 1406
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:199 → 252
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1789 → 1960
      CHDCT2; CHDCT2 (NUC038) domain

    15. XM_036156568.1 → XP_036012461.1  chromodomain-helicase-DNA-binding protein 3 isoform X9

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:760 → 1314
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1550 → 1735
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:423 → 465
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:499 → 541
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:669 → 723
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:546 → 624
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:777 → 1008
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1419 → 1558
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1355 → 1398
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:199 → 252
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1778 → 1904
      CHDCT2; CHDCT2 (NUC038) domain

    16. XM_036156567.1 → XP_036012460.1  chromodomain-helicase-DNA-binding protein 3 isoform X8

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:761 → 1315
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1551 → 1736
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:424 → 466
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:500 → 542
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:670 → 724
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:547 → 625
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:778 → 1009
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1420 → 1559
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1356 → 1399
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1779 → 1905
      CHDCT2; CHDCT2 (NUC038) domain

    17. XM_036156566.1 → XP_036012459.1  chromodomain-helicase-DNA-binding protein 3 isoform X6

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      PLN03142
      Location:765 → 1319
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      PHA03169
      Location:1555 → 1740
      PHA03169; hypothetical protein; Provisional
      cd15531
      Location:428 → 470
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:504 → 546
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:674 → 728
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:551 → 629
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:782 → 1013
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1424 → 1563
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1360 → 1403
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1783 → 1909
      CHDCT2; CHDCT2 (NUC038) domain

    18. XM_006532885.2 → XP_006532948.1  chromodomain-helicase-DNA-binding protein 3 isoform X11

      UniProtKB/TrEMBL
      F7C528
      Conserved Domains (11) summary
      TIGR02927
      Location:1572 → 1724
      SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
      PLN03142
      Location:771 → 1325
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd15531
      Location:434 → 476
      PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd15532
      Location:510 → 552
      PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
      cd18662
      Location:680 → 734
      CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18667
      Location:557 → 635
      CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
      cd18055
      Location:788 → 1019
      DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
      pfam06461
      Location:1430 → 1569
      DUF1086; Domain of Unknown Function (DUF1086)
      pfam06465
      Location:1364 → 1407
      DUF1087; Domain of Unknown Function (DUF1087)
      pfam08073
      Location:200 → 253
      CHDNT; CHDNT (NUC034) domain
      pfam08074
      Location:1755 → 1882
      CHDCT2; CHDCT2 (NUC038) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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