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    SPR28 septin SPR28 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851804, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SPR28
    Official Full Name
    septin SPR28
    Primary source
    SGD:S000002626
    Locus tag
    YDR218C
    See related
    AllianceGenome:SGD:S000002626; FungiDB:YDR218C; VEuPathDB:YDR218C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable GTPase activity; molecular adaptor activity; and structural molecule activity. Involved in ascospore formation. Located in ascospore wall; prospore membrane; and spindle. Part of septin complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SPR28 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (903781..905052, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene DNA-binding transcription factor ADR1 Neighboring gene chromatin-binding protein RAD9 Neighboring gene Mfb1p Neighboring gene Gtb1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells. De Virgilio C, et al. Microbiology (Reading), 1996 Oct. PMID 8885406
    2. Septins localize to microtubules during nutritional limitation in Saccharomyces cerevisiae. Pablo-Hernando ME, et al. BMC Cell Biol, 2008 Oct 1. PMID 18826657, Free PMC Article
    3. Assembly, molecular organization, and membrane-binding properties of development-specific septins. Garcia G 3rd, et al. J Cell Biol, 2016 Feb 29. PMID 26929450, Free PMC Article
    4. Analysis of septins across kingdoms reveals orthology and new motifs. Pan F, et al. BMC Evol Biol, 2007 Jul 1. PMID 17601340, Free PMC Article
    5. Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae. Tun NM, et al. Metallomics, 2014 Aug. PMID 24926745

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural molecule activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular bud neck septin ring organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoskeleton-dependent cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in division septum assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to bud neck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in ascospore wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell division site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in meiotic spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of septin complex HDA PubMed 
    part_of septin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of septin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of septin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in septin ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    septin SPR28
    NP_010504.1
    • Sporulation-specific homolog of the CDC3/10/11/12 family of genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation; the yeast CDC3/10/11/12 family is a family of bud neck microfilament genes

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      903781..905052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180526.1 → NP_010504.1  TPA: septin SPR28 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010504.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSK1, Q04921
      UniProtKB/TrEMBL
      A6ZYH3, B3LG68, C7GVD2, C8Z5C9, N1P6L3
      Conserved Domains (1) summary
      COG5019
      Location:16 → 423
      CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04921.1

    Gene LinkOut

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