U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    OR5B2 olfactory receptor family 5 subfamily B member 2 [ Homo sapiens (human) ]

    Gene ID: 390190, updated on 10-Dec-2024

    Summary

    Official Symbol
    OR5B2provided by HGNC
    Official Full Name
    olfactory receptor family 5 subfamily B member 2provided by HGNC
    Primary source
    HGNC:HGNC:8323
    See related
    Ensembl:ENSG00000172365 AllianceGenome:HGNC:8323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OST073; OR11-240
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See OR5B2 in Genome Data Viewer
    Location:
    11q12.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (58421238..58428121, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (58371159..58378042, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (58188711..58195594, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily B member 15 pseudogene Neighboring gene olfactory receptor family 5 subfamily B member 3 Neighboring gene olfactory receptor family 5 subfamily B member 12 Neighboring gene uncharacterized LOC105369313 Neighboring gene olfactory receptor family 5 subfamily B member 21

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity  
    enables odorant binding  
    enables olfactory receptor activity  
    Component Evidence Code Pubs
    located_in plasma membrane  

    General protein information

    Preferred Names
    olfactory receptor 5B2
    Names
    olfactory receptor OR11-240

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005566.3NP_001005566.1  olfactory receptor 5B2

      See identical proteins and their annotated locations for NP_001005566.1

      Status: VALIDATED

      Source sequence(s)
      AP002345, KC877418
      Consensus CDS
      CCDS31550.1
      UniProtKB/Swiss-Prot
      B2RNJ6, B9EGY7, Q6IEV7, Q8NGF5, Q96R09
      UniProtKB/TrEMBL
      A0A126GVM9
      Related
      ENSP00000493419.1, ENST00000641342.2
      Conserved Domains (2) summary
      pfam00001
      Location:39288
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29303
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      58421238..58428121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      58371159..58378042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.