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    Fbxl8 F-box and leucine-rich repeat protein 8 [ Mus musculus (house mouse) ]

    Gene ID: 50788, updated on 27-Dec-2024

    Summary

    Official Symbol
    Fbxl8provided by MGI
    Official Full Name
    F-box and leucine-rich repeat protein 8provided by MGI
    Primary source
    MGI:MGI:1354697
    See related
    Ensembl:ENSMUSG00000033313 AllianceGenome:MGI:1354697
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FBL8
    Summary
    Is expressed in several structures, including adrenal gland; genitourinary system; liver; lung; and spleen. Orthologous to human FBXL8 (F-box and leucine rich repeat protein 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in colon adult (RPKM 13.7), duodenum adult (RPKM 10.0) and 19 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Fbxl8 in Genome Data Viewer
    Location:
    8 D3; 8 53.04 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (105991280..105995958)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105264648..105269326)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene phagosome assembly factor 1 Neighboring gene STARR-positive B cell enhancer mm9_chr8:107778026-107778327 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Neighboring gene TNFRSF1A-associated via death domain Neighboring gene STARR-positive B cell enhancer ABC_E8260 Neighboring gene heat shock transcription factor 4 Neighboring gene nucleolar protein 3 (apoptosis repressor with CARD domain) Neighboring gene microtubule associated tyrosine carboxypeptidase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    F-box/LRR-repeat protein 8
    Names
    F-box protein FBL8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015821.2NP_056636.2  F-box/LRR-repeat protein 8

      See identical proteins and their annotated locations for NP_056636.2

      Status: VALIDATED

      Source sequence(s)
      AC124584, CX222518
      Consensus CDS
      CCDS22595.1
      UniProtKB/Swiss-Prot
      Q8CIG9, Q9QZN7
      UniProtKB/TrEMBL
      Q3TD55
      Related
      ENSMUSP00000038638.6, ENSMUST00000036221.12
      Conserved Domains (2) summary
      sd00034
      Location:103136
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:533
      F-box-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      105991280..105995958
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)