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    Zfp990 zinc finger protein 990 [ Mus musculus (house mouse) ]

    Gene ID: 101056073, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp990provided by MGI
    Official Full Name
    zinc finger protein 990provided by MGI
    Primary source
    MGI:MGI:3652161
    See related
    Ensembl:ENSMUSG00000078503 AllianceGenome:MGI:3652161
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13225
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Zfp990 in Genome Data Viewer
    Location:
    4 E1; 4 78.2 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (145237329..145265751)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (145510759..145538251)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12026 Neighboring gene SNF2 related chromatin remodeling ATPase 5, pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_12028 Neighboring gene STARR-seq mESC enhancer starr_12029 Neighboring gene STARR-seq mESC enhancer starr_12030 Neighboring gene STARR-seq mESC enhancer starr_12031 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145147852-145148153 Neighboring gene vomeronasal receptor Vmn2r-ps14 Neighboring gene high mobility group protein B1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 501-like
    Names
    novel KRAB box containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001324553.1 → NP_001311482.1  zinc finger protein 501-like

      Status: VALIDATED

      Source sequence(s)
      AL606963, AL713973, BX323552
      Consensus CDS
      CCDS84822.1
      UniProtKB/TrEMBL
      B1AVN5
      Related
      ENSMUSP00000101368.2, ENSMUST00000105742.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      145237329..145265751
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163558.1 → XP_036019451.1  zinc finger protein 501-like isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:152 → 515
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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