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    Or52ab2 olfactory receptor family 52 subfamily AB member 2 [ Mus musculus (house mouse) ]

    Gene ID: 258135, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or52ab2provided by MGI
    Official Full Name
    olfactory receptor family 52 subfamily AB member 2provided by MGI
    Primary source
    MGI:MGI:3030431
    See related
    Ensembl:ENSMUSG00000073952 AllianceGenome:MGI:3030431
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR23-2; Olfr597; GA_x5J8B7TU1BB-380-666
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or52ab2 in Genome Data Viewer
    Location:
    7 E3; 7 54.85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (102969620..102970567)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (103320413..103321360)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 17-like D Neighboring gene STARR-seq mESC enhancer starr_19720 Neighboring gene olfactory receptor family 52 subfamily E member 19 Neighboring gene olfactory receptor family 52 subfamily AB member 7 Neighboring gene olfactory receptor family 52 subfamily AB member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 597
    Names
    GA_x6K02T2PBJ9-6029614-6030561
    olfactory receptor GA_x5J8B7TU1BB-380-666
    olfactory receptor MOR23-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011845.2 → NP_001011845.2  olfactory receptor 597

      Status: VALIDATED

      Source sequence(s)
      AC108410
      Consensus CDS
      CCDS52336.1
      UniProtKB/TrEMBL
      L7N224, Q7TRR3
      Related
      ENSMUSP00000095804.3, ENSMUST00000098203.4
      Conserved Domains (2) summary
      pfam00001
      Location:55 → 293
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:54 → 308
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      102969620..102970567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001630.1: Suppressed sequence

      Description
      NG_001630.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.

    2. NG_002022.1: Suppressed sequence

      Description
      NG_002022.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.
    Nucleotide Protein
    Heading Accession and Version

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